BACKGROUND: Information on male potency in lymphoma survivors is insufficient. In this study, we assessed male sexual function and serum gonadotropins in successfully treated lymphoma patients. MATERIALS AND METHODS: Fifty-nine patients treated for Hodgkin's lymphoma (HL) or non-HL (NHL) with chemotherapy +/- radiotherapy were included in the study. RESULTS: The mean age (+/-standard deviation) of the patients was 40.2 +/- 11.0 (range, 18-55 years). Thirty-eight (64.4%) had HL and 21 (35.6%) NHL. According to the International Index of Erectile Function (IIEF) score, 61.0% had some degree of erectile dysfunction (ED; IIEF score < 26): 33.9% had mild ED (IIEF score 17-25), 15.2% moderate ED (IIEF score 11-16), and 11.9% severe ED (IIEF score 6-10). Age distribution was similar in patients with ED and those with normal erectile function. Presence of ED and its grade were not different between HL and NHL patients. Nine (18.4%) of 49 patients had an elevated follicle-stimulating hormone, 7 (14.2%) had elevated luteinizing hormone, and 3 (6.1%) had decreased testosterone levels. These hormonal abnormalities did not affect the presence of ED and its severity. CONCLUSIONS: Overall, 61.0% of men in our study had ED according to IIEF. Clinicians should be aware of this problem in lymphoma survivors and offer these patients adequate treatment options.
BACKGROUND: Information on male potency in lymphoma survivors is insufficient. In this study, we assessed male sexual function and serum gonadotropins in successfully treated lymphomapatients. MATERIALS AND METHODS: Fifty-nine patients treated for Hodgkin's lymphoma (HL) or non-HL (NHL) with chemotherapy +/- radiotherapy were included in the study. RESULTS: The mean age (+/-standard deviation) of the patients was 40.2 +/- 11.0 (range, 18-55 years). Thirty-eight (64.4%) had HL and 21 (35.6%) NHL. According to the International Index of Erectile Function (IIEF) score, 61.0% had some degree of erectile dysfunction (ED; IIEF score < 26): 33.9% had mild ED (IIEF score 17-25), 15.2% moderate ED (IIEF score 11-16), and 11.9% severe ED (IIEF score 6-10). Age distribution was similar in patients with ED and those with normal erectile function. Presence of ED and its grade were not different between HL and NHL patients. Nine (18.4%) of 49 patients had an elevated follicle-stimulating hormone, 7 (14.2%) had elevated luteinizing hormone, and 3 (6.1%) had decreased testosterone levels. These hormonal abnormalities did not affect the presence of ED and its severity. CONCLUSIONS: Overall, 61.0% of men in our study had ED according to IIEF. Clinicians should be aware of this problem in lymphoma survivors and offer these patients adequate treatment options.
Authors: S Viviani; G Ragni; A Santoro; L Perotti; E Caccamo; E Negretti; P Valagussa; G Bonadonna Journal: Eur J Cancer Date: 1991 Impact factor: 9.162
Authors: Corien Eeltink; Alaa Embaby; Luca Incrocci; Johannes C F Ket; Sarah J Liptrott; Irma Verdonck-de Leeuw; Sonja Zweegman Journal: Support Care Cancer Date: 2022-01-21 Impact factor: 3.603
Authors: Damiano Pizzol; Tao Xiao; Lee Smith; Guillermo F López Sánchez; Andrea Garolla; Christopher Parris; Yvonne Barnett; Petre Cristian Ilie; Pinar Soysal; Jae Il Shin; Mark A Tully; Lin Yang; Nicola Veronese; Igor Grabovac Journal: Br J Gen Pract Date: 2021-04-29 Impact factor: 5.386
Authors: Leslie R Schover; Marleen van der Kaaij; Eleonora van Dorst; Carien Creutzberg; Eric Huyghe; Cecilie E Kiserud Journal: EJC Suppl Date: 2014-05-29