Literature DB >> 17658922

Theoretical models for chronotherapy: periodic perturbations in funnel chaos type.

Juvencio Alberto Betancourt-Mar1, Jose Manuel Nieto-Villar.   

Abstract

In this work, the Rössler system is used as a model for chrono therapy. We applied a periodic perturbation to the y variable to take the Rössler system from a chaotic behavior to a simple periodic one, varying the period and amplitude of forcing. Two types of chaos were considered, spiral and funnel chaos. As a result, the periodical windows reduced their areas as the funnel chaos character increased in the system. Funnel chaos, in this chrono therapy model, could be considered as a later state of a dynamical disease, more irregular and difficult to suppress.

Mesh:

Year:  2007        PMID: 17658922     DOI: 10.3934/mbe.2007.4.177

Source DB:  PubMed          Journal:  Math Biosci Eng        ISSN: 1547-1063            Impact factor:   2.080


  2 in total

Review 1.  Chronopharmaceutical drug delivery systems: Hurdles, hype or hope?

Authors:  Bi-Botti C Youan
Journal:  Adv Drug Deliv Rev       Date:  2010-05-12       Impact factor: 15.470

2.  Complexity in Biological Organization: Deconstruction (and Subsequent Restating) of Key Concepts.

Authors:  Mariano Bizzarri; Oleg Naimark; José Nieto-Villar; Valeria Fedeli; Alessandro Giuliani
Journal:  Entropy (Basel)       Date:  2020-08-12       Impact factor: 2.524

  2 in total

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