Literature DB >> 17658852

Diastereoselective formal synthesis of a monoterpene alkaloid, (-)-incarvilline.

Toshio Honda1, Kyosuke Kaneda.   

Abstract

Diastereoselective formal synthesis of a monoterpene alkaloid, (-)-incarvilline, the key intermediate for the synthesis of (-)-incarvillateine, was achieved by using an intramolecular Pauson-Khand reaction of (S)-N-[(E)-2-butenyl]-N-(3-butynyl-2-methoxymethoxy)-p-toluenesulfonamide as a key step.

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Year:  2007        PMID: 17658852     DOI: 10.1021/jo0709091

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Asymmetric synthesis of (-)-incarvillateine employing an intramolecular alkylation via Rh-catalyzed olefinic C-H bond activation.

Authors:  Andy S Tsai; Robert G Bergman; Jonathan A Ellman
Journal:  J Am Chem Soc       Date:  2008-04-29       Impact factor: 15.419

  1 in total

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