Literature DB >> 17658836

Organocatalytic conjugate addition of formaldehyde N,N-dialkylhydrazones to beta,gamma-unsaturated alpha-keto esters.

Raquel P Herrera1, David Monge, Eloísa Martín-Zamora, Rosario Fernandez, José M Lassaletta.   

Abstract

(1S,2R)-1-Aminoindan-2-ol-derived thioureas behave as efficient H-bonding organocatalysts for the nucleophilic conjugate addition of formaldehyde hydrazones to beta,gamma-unsaturated alpha-keto esters as enoate surrogates, affording the corresponding adducts in good yields and enantioselectivities.

Entities:  

Year:  2007        PMID： 17658836     DOI： 10.1021/ol071292c

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  A Novel Bis-Thiourea Organocatalyst for the Asymmetric Aza-Henry Reaction.

Authors:  Constantinos Rampalakos; William D Wulff
Journal:  Adv Synth Catal       Date:  2008-08-04       Impact factor: 5.837

2.  Gold(I)-Mediated Thiourea Organocatalyst Activation: A Synergic Effect for Asymmetric Catalysis.

Authors:  Anabel Izaga; Raquel P Herrera; M Concepción Gimeno
Journal:  ChemCatChem       Date:  2017-03-23       Impact factor: 5.686

3.  N,N-Dialkylhydrazones as Versatile Umpolung Reagents in Enantioselective Anion-Binding Catalysis.

Authors:  Melania Gómez-Martínez; María Del Carmen Pérez-Aguilar; Dariusz G Piekarski; Constantin G Daniliuc; Olga García Mancheño
Journal:  Angew Chem Int Ed Engl       Date:  2021-01-15       Impact factor: 15.336

4.  Asymmetric bioreduction of activated carbon-carbon double bonds using Shewanella yellow enzyme (SYE-4) as novel enoate reductase.

Authors:  Naseem Iqbal; Florian Rudroff; Ann Brigé; Jozef Van Beeumen; Marko D Mihovilovic
Journal:  Tetrahedron       Date:  2012-09-16       Impact factor: 2.457

5.  Squaramide-catalyzed enantioselective Michael addition of masked acyl cyanides to substituted enones.

Authors:  Kin S Yang; Antoinette E Nibbs; Yunus E Türkmen; Viresh H Rawal
Journal:  J Am Chem Soc       Date:  2013-10-17       Impact factor: 15.419

Review 6.  The aminoindanol core as a key scaffold in bifunctional organocatalysts.

Authors:  Isaac G Sonsona; Eugenia Marqués-López; Raquel P Herrera
Journal:  Beilstein J Org Chem       Date:  2016-03-14       Impact factor: 2.883
  6 in total

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