BACKGROUND: Depression is a public health problem, due to its high prevalence and its associated disability. AIM: To compare a pharmacological intervention for depression controlled by phone from a central level (TM) and the usual treatment (TH) in a randomized clinical trial. MATERIAL AND METHODS: Three hundred and forty five women, aged 22 to 59 years were studied. They were randomly assigned to receive the usual therapy or a pharmacological intervention with periodical telephone contacts with medical collaboration personnel, to reinforce compliance with treatment and educate about the disease. Women were blindly evaluated at 3 and 6 months with the Hamilton depression rating score (HDRS) and the SF-36 to assess depressive symptoms and quality of life, respectively. RESULTS: In both evaluations, improvement was significantly greater in the TM group than the TH group. At 3 months, improvement was higher in the TM group in the subscales of physical function, pain, general health, energy, emotional role, mental health and standardized physical and psychic scales of SF-36. At 6 months, this significant difference in favour of TM was maintained for energy, mental health and the standardized psychic scale. CONCLUSIONS: A telephone reinforcement improves the outcomes of treatments for depression.
RCT Entities:
BACKGROUND:Depression is a public health problem, due to its high prevalence and its associated disability. AIM: To compare a pharmacological intervention for depression controlled by phone from a central level (TM) and the usual treatment (TH) in a randomized clinical trial. MATERIAL AND METHODS: Three hundred and forty five women, aged 22 to 59 years were studied. They were randomly assigned to receive the usual therapy or a pharmacological intervention with periodical telephone contacts with medical collaboration personnel, to reinforce compliance with treatment and educate about the disease. Women were blindly evaluated at 3 and 6 months with the Hamilton depression rating score (HDRS) and the SF-36 to assess depressive symptoms and quality of life, respectively. RESULTS: In both evaluations, improvement was significantly greater in the TM group than the TH group. At 3 months, improvement was higher in the TM group in the subscales of physical function, pain, general health, energy, emotional role, mental health and standardized physical and psychic scales of SF-36. At 6 months, this significant difference in favour of TM was maintained for energy, mental health and the standardized psychic scale. CONCLUSIONS: A telephone reinforcement improves the outcomes of treatments for depression.
Authors: Daisy R Singla; Brandon A Kohrt; Laura K Murray; Arpita Anand; Bruce F Chorpita; Vikram Patel Journal: Annu Rev Clin Psychol Date: 2017-05-08 Impact factor: 18.561
Authors: John A Naslund; Kelly A Aschbrenner; Ricardo Araya; Lisa A Marsch; Jürgen Unützer; Vikram Patel; Stephen J Bartels Journal: Lancet Psychiatry Date: 2017-04-19 Impact factor: 27.083
Authors: J M Shultz; H Verdeli; Á Gómez Ceballos; L J Hernandez; Z Espinel; L Helpman; Y Neria; R Araya Journal: Glob Ment Health (Camb) Date: 2019-12-02
Authors: Vania Martínez; Graciela Rojas; Pablo Martínez; Pedro Zitko; Matías Irarrázaval; Carolina Luttges; Ricardo Araya Journal: J Med Internet Res Date: 2018-01-31 Impact factor: 5.428
Authors: Graciela Rojas; Viviana Guajardo; Pablo Martínez; Ariel Castro; Rosemarie Fritsch; Markus Moessner; Stephanie Bauer Journal: J Med Internet Res Date: 2018-04-30 Impact factor: 5.428