Literature DB >> 17653293

Empirical evaluation of language disorder in schizophrenia.

Massoud Stephane1, Giuseppe Pellizzer, Charles R Fletcher, Kate McClannahan.   

Abstract

OBJECTIVE: Studies of the content of speech and of verbal hallucinations in schizophrenia point to dysfunction at multiple levels of language. In this study, we empirically evaluated language processes.
METHODS: We examined the performance of 22 schizophrenia patients and 11 healthy control subjects with procedures designed to explore the sublexical, lexical, semantic, syntactic and discourse levels of language processing.
RESULTS: Schizophrenia patients exhibit impairment in the recognition of incorrect, but not correct, linguistic stimuli at all but the sublexical level of language processing. The patients were not impaired in the recognition of nonlinguistic stimuli.
CONCLUSION: This language-specific differential impairment could explain speech abnormalities in schizophrenia. The nonrecognition of incorrect linguistic information would prevent patients from correcting the abnormal speech they may occasionally produce. A model of decreased power of linguistic computations (reduced number of operations) adequately accounts for this differential impairment.

Entities:  

Mesh:

Year:  2007        PMID: 17653293      PMCID: PMC1911189     

Source DB:  PubMed          Journal:  J Psychiatry Neurosci        ISSN: 1180-4882            Impact factor:   6.186


  45 in total

1.  Imaging auditory verbal hallucinations during their occurrence.

Authors:  M Stephane; M Folstein; E Matthew; T C Hill
Journal:  J Neuropsychiatry Clin Neurosci       Date:  2000       Impact factor: 2.198

2.  Apprehending schizophrenic discourse: a structural analysis of the listener's task.

Authors:  R E Hoffman; L Kirstein; S Stopek; D V Cicchetti
Journal:  Brain Lang       Date:  1982-03       Impact factor: 2.381

3.  Thought, language, and communication disorders. I. Clinical assessment, definition of terms, and evaluation of their reliability.

Authors:  N C Andreasen
Journal:  Arch Gen Psychiatry       Date:  1979-11

4.  Thought, language, and communication disorders. II. Diagnostic significance.

Authors:  N C Andreasen
Journal:  Arch Gen Psychiatry       Date:  1979-11

5.  An investigation of the integrity of semantic boundaries in schizophrenia.

Authors:  B Elvevåg; T Weickert; M Wechsler; R Coppola; D R Weinberger; T E Goldberg
Journal:  Schizophr Res       Date:  2002-01-15       Impact factor: 4.939

Review 6.  Auditory verbal hallucinations and dysfunction of the neural substrates of speech.

Authors:  M Stephane; S Barton; N N Boutros
Journal:  Schizophr Res       Date:  2001-05-30       Impact factor: 4.939

7.  Context-dependent information processing in patients with schizophrenia.

Authors:  N Bazin; P Perruchet; M C Hardy-Bayle; A Feline
Journal:  Schizophr Res       Date:  2000-09-29       Impact factor: 4.939

8.  Dissociation between conflict detection and error monitoring in the human anterior cingulate cortex.

Authors:  Diane Swick; And U Turken
Journal:  Proc Natl Acad Sci U S A       Date:  2002-11-27       Impact factor: 11.205

Review 9.  Semantic priming in schizophrenia: a review and synthesis.

Authors:  Michael J Minzenberg; Beth A Ober; Sophia Vinogradov
Journal:  J Int Neuropsychol Soc       Date:  2002-07       Impact factor: 2.892

10.  The internal structure of the phenomenology of auditory verbal hallucinations.

Authors:  Massoud Stephane; Paul Thuras; Henry Nasrallah; Apostolos P Georgopoulos
Journal:  Schizophr Res       Date:  2003-06-01       Impact factor: 4.939

View more
  4 in total

1.  Semantics, pragmatics, and formal thought disorders in people with schizophrenia.

Authors:  Carlos Salavera; Miguel Puyuelo; José L Antoñanzas; Pilar Teruel
Journal:  Neuropsychiatr Dis Treat       Date:  2013-02-07       Impact factor: 2.570

2.  Bridging the Gap between Genes and Language Deficits in Schizophrenia: An Oscillopathic Approach.

Authors:  Elliot Murphy; Antonio Benítez-Burraco
Journal:  Front Hum Neurosci       Date:  2016-08-23       Impact factor: 3.169

3.  The FOXP2-Driven Network in Developmental Disorders and Neurodegeneration.

Authors:  Franz Oswald; Patricia Klöble; André Ruland; David Rosenkranz; Bastian Hinz; Falk Butter; Sanja Ramljak; Ulrich Zechner; Holger Herlyn
Journal:  Front Cell Neurosci       Date:  2017-07-26       Impact factor: 5.505

4.  The Oscillopathic Nature of Language Deficits in Autism: From Genes to Language Evolution.

Authors:  Antonio Benítez-Burraco; Elliot Murphy
Journal:  Front Hum Neurosci       Date:  2016-03-18       Impact factor: 3.169

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.