Literature DB >> 17650514

Functional conservation between CRABS CLAW orthologues from widely diverged angiosperms.

Chloe Fourquin1, Marion Vinauger-Douard, Pierre Chambrier, Annick Berne-Dedieu, Charles P Scutt.   

Abstract

BACKGROUND AND AIMS: CRABS CLAW (CRC) encodes a transcription factor of the YABBY family that plays important roles in carpel and nectary development in Arabidopsis thaliana. Combined evolutionary and developmental studies suggest an ancestor of the CRC gene to have controlled carpel development in the last common ancestor of the angiosperms. Roles for CRC orthologues in leaf development and carpel specification in rice, and in nectary development in core eudicots, have accordingly been interpreted as derived. The aim of this study was to assess the capacity of CRC orthologues from a basal angiosperm and from rice to complement CRC mutants of arabidopsis. These experiments were designed to test the hypothesized ancestral role of CRC in the angiosperms, and to indicate whether putatively novel roles of various CRC orthologues resulted from changes to their encoded proteins, or from other molecular evolutionary events.
METHODS: The crc-1 mutant of arabidopsis was genetically transformed with the coding sequences of various CRC orthologues, and with paralogous YABBY coding sequences, under the control of the arabidopsis CRC promoter. The phenotypes of transformed plants were assessed to determine the degree of complementation of the crc-1 mutant phenotype in carpel fusion, carpel form and nectary development. KEY
RESULTS: The CRC orthologue from the basal angiosperm Amborella trichopoda partially complemented the crc-1 mutant phenotype in carpels, but not in nectaries. The CRC orthologue from rice partially complemented all aspects of the crc-1 mutant phenotype. Though most non-CRC YABBY coding sequences did not complement crc-1 mutant phenotypes, YABBY2 (YAB2) proved to be an exception.
CONCLUSIONS: The data support a hypothesized ancestral role for CRC in carpel development and suggest that novel roles for CRC orthologues in monocots and in core eudicots resulted principally from molecular changes other than those affecting their coding sequences.

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Year:  2007        PMID: 17650514      PMCID: PMC2533609          DOI: 10.1093/aob/mcm136

Source DB:  PubMed          Journal:  Ann Bot        ISSN: 0305-7364            Impact factor:   4.357


  15 in total

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9.  CRABS CLAW, a gene that regulates carpel and nectary development in Arabidopsis, encodes a novel protein with zinc finger and helix-loop-helix domains.

Authors:  J L Bowman; D R Smyth
Journal:  Development       Date:  1999-06       Impact factor: 6.868

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Authors:  J Alvarez; D R Smyth
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  11 in total

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5.  The Role of SHI/STY/SRS Genes in Organ Growth and Carpel Development Is Conserved in the Distant Eudicot Species Arabidopsis thaliana and Nicotiana benthamiana.

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10.  Genome-wide identification and analysis of the YABBY gene family in Moso Bamboo (Phyllostachys edulis (Carrière) J. Houz).

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