Literature DB >> 17650480

[Progress on the research of microRNAs and its function in humans and animals].

Xi-Hui Sheng1, Li-Xin Du.   

Abstract

MicroRNAs, a class of noncoding RNA of approximately 22 nucleotides, can regulate gene expression by binding to the region of 3' UTR of the target mRNAs. To date, it has been demonstrated for organism that miRNAs play an important role in growth, development,and occurrence of disease. This paper introduces the character and the active mechanism of miRNAs, and the newest progress in the research on the function of microRNA, the identification of microRNA gene and the prediction of target gene also are summarized here.

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Year:  2007        PMID: 17650480     DOI: 10.1360/yc-007-0651

Source DB:  PubMed          Journal:  Yi Chuan        ISSN: 0253-9772


  2 in total

1.  Comparative genomic approach reveals novel conserved microRNAs in Inner Mongolia cashmere goat skin and longissimus dorsi.

Authors:  Rui Su; Shaoyin Fu; Yanjun Zhang; Ruijun Wang; Yanhong Zhou; Jinquan Li; Wenguang Zhang
Journal:  Mol Biol Rep       Date:  2014-11-22       Impact factor: 2.316

2.  The antileukemia activity of natural product HQ17(3) is possibly associated with downregulation of miR-17-92 cluster.

Authors:  Ya-Chun Liao; Tzu-Heng Lin; Chih-Ying Chen; Shwu-Bin Lin; Lo-Chun Au
Journal:  Biomed Res Int       Date:  2014-07-22       Impact factor: 3.411

  2 in total

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