Literature DB >> 1764946

Antifertility activity of volatile fraction of neem oil.

S S Riar1, C Devakumar, R C Sawhney, G Ilavazhagan, J Bardhan, A K Kain, P Thomas, R Singh, B Singh, R Parshad.   

Abstract

NIM-76, the odorous and volatile fraction of neem oil, was investigated for its antifertility activity in vivo in rats, rabbits and rhesus monkeys. The drug is effective when applied before coitus but not so when applied during post-coital stages. It, therefore, appears to act mainly by its spermicidal effect. No alteration in the estradiol (E2) and progesterone (P) values was observed after the application of the drug in monkeys.

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Year:  1991        PMID: 1764946     DOI: 10.1016/0010-7824(91)90021-7

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  3 in total

1.  Minor and trace elemental determination in the Indian herbal and other medicinal preparations.

Authors:  D L Samudralwar; A N Garg
Journal:  Biol Trace Elem Res       Date:  1996-08       Impact factor: 3.738

2.  Antifertility potential of Neem flower extract on adult female Sprague-Dawley rats.

Authors:  S C Gbotolorun; A A Osinubi; C C Noronha; A O Okanlawon
Journal:  Afr Health Sci       Date:  2008-09       Impact factor: 0.927

3.  Neem oil inhibits two-cell embryo development and trophectoderm attachment and proliferation in vitro.

Authors:  S C Juneja; T Pfeifer; R S Williams; N Chegini
Journal:  J Assist Reprod Genet       Date:  1994-09       Impact factor: 3.412

  3 in total

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