Literature DB >> 17647097

Severe vitamin D-deficiency and the health of North China children.

Mark A Strand1, Judith Perry, Jinping Zhao, Philip R Fischer, Jianping Yang, Sihan Li.   

Abstract

OBJECTIVES: To determine the health and nutritional status of rural Chinese children ages 12-24 months.
METHODS: This study used a cross-sectional design with a longitudinal component. Anthropometry and blood chemistry were measured on each child twice (n = 250). Caretaker knowledge and behaviors that relate to the child's health and diet were evaluated by interview.
RESULTS: Children were taken outdoors at an average age of 131.8 days. 65.3% of surveyed children had serum 25-OH-D levels less than 12 ng/ml in the spring. This declined to 2.8% in the fall. Mean blood lead levels were 15.7 +/- 11.0 microg/dl in the spring declining to 12.4 +/- 12.5 microg/dl in the fall (t = 6.47, P = 0.000). This still left 63.5 and 54.9% of the children with toxic blood lead levels in spring and fall. Rates of respiratory disease declined significantly from spring to fall. A summer outdoors remarkably improved vitamin D-deficiency and lead toxicity. However, nutritional status worsened as during the summer diet was unable to keep up with growth and increased nutritional demand. From spring to fall serum zinc declined from 0.77 +/- 0.19 to 0.66 +/- 0.21 microg/ml (t = 3.33, P = 0.001) and blood hemoglobin declined from 12.5 +/- 1.2 to 12.0 +/- 1.2 gm/dl (t = 4.07, P = 0.000).
CONCLUSIONS: Northern climate and cloistering of children creates a host of health risks for north China children. Vitamin D-deficiency, lead poisoning and respiratory disease are significantly worse during the winter months. These children need vitamin D supplementation during the winter and improved overall nutritional status during the summer to maintain ideal growth and development.

Entities:  

Mesh:

Year:  2007        PMID: 17647097     DOI: 10.1007/s10995-007-0250-z

Source DB:  PubMed          Journal:  Matern Child Health J        ISSN: 1092-7875


  25 in total

1.  Strengthening governance for global health research. Ways of getting vitamin A to children in developing countries have to be improved.

Authors:  J Black; B Loff
Journal:  BMJ       Date:  2001-04-21

2.  Ultraviolet B and blood pressure.

Authors:  R Krause; M Bühring; W Hopfenmüller; M F Holick; A M Sharma
Journal:  Lancet       Date:  1998-08-29       Impact factor: 79.321

3.  Vitamin D concentrations in Asian children living in England. Limited vitamin D intake and use of sunscreens may lead to rickets.

Authors:  S Zlotkin
Journal:  BMJ       Date:  1999-05-22

Review 4.  Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease.

Authors:  Michael F Holick
Journal:  Am J Clin Nutr       Date:  2004-12       Impact factor: 7.045

5.  Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study.

Authors:  R J Wilkinson; M Llewelyn; Z Toossi; P Patel; G Pasvol; A Lalvani; D Wright; M Latif; R N Davidson
Journal:  Lancet       Date:  2000-02-19       Impact factor: 79.321

6.  Case-control study of the role of nutritional rickets in the risk of developing pneumonia in Ethiopian children.

Authors:  L Muhe; S Lulseged; K E Mason; E A Simoes
Journal:  Lancet       Date:  1997-06-21       Impact factor: 79.321

Review 7.  Zinc and immune function: the biological basis of altered resistance to infection.

Authors:  A H Shankar; A S Prasad
Journal:  Am J Clin Nutr       Date:  1998-08       Impact factor: 7.045

8.  Childhood lead poisoning in China.

Authors:  X Shen; J F Rosen; D Guo; S Wu
Journal:  Sci Total Environ       Date:  1996-03-15       Impact factor: 7.963

9.  Declining blood lead levels and changes in cognitive function during childhood: the Port Pirie Cohort Study.

Authors:  S Tong; P A Baghurst; M G Sawyer; J Burns; A J McMichael
Journal:  JAMA       Date:  1998-12-09       Impact factor: 56.272

10.  Diagnosis of rickets and reassessment of prevalence among rural children in northern China.

Authors:  Mark A Strand; Judith Perry; Meimei Jin; David P Tracer; Philip R Fischer; Peiying Zhang; Weiping Xi; Sihan Li
Journal:  Pediatr Int       Date:  2007-04       Impact factor: 1.524

View more
  5 in total

1.  Vitamin D fortification of growing up milk prevents decrease of serum 25-hydroxyvitamin D concentrations during winter: a clinical intervention study in Germany.

Authors:  Jürgen Hower; Anette Knoll; Kristin L Ritzenthaler; Claudia Steiner; Regina Berwind
Journal:  Eur J Pediatr       Date:  2013-07-13       Impact factor: 3.183

2.  Vitamin D status among infants, children, and adolescents in southeastern China.

Authors:  Ling-Li Wang; Hui-Yan Wang; Huai-Kai Wen; Hong-Qun Tao; Xiao-Wei Zhao
Journal:  J Zhejiang Univ Sci B       Date:  2016-07       Impact factor: 3.066

3.  High prevalence of vitamin D deficiency among children aged 1 month to 16 years in Hangzhou, China.

Authors:  Zhiwei Zhu; Jianying Zhan; Jie Shao; Weijun Chen; Liqin Chen; Wenhao Li; Chai Ji; Zhengyan Zhao
Journal:  BMC Public Health       Date:  2012-02-14       Impact factor: 3.295

4.  Dietary Diversity among Preschoolers: A Cross-Sectional Study in Poor, Rural, and Ethnic Minority Areas of Central South China.

Authors:  Jieying Bi; Chengfang Liu; Shaoping Li; Zhenya He; Kevin Chen; Renfu Luo; Zimeiyi Wang; Yanying Yu; Haiquan Xu
Journal:  Nutrients       Date:  2019-03-06       Impact factor: 5.717

5.  Association of serum 25-hydroxyvitamin D status with bone mineral density in 0-7 year old children.

Authors:  Yanrong Fu; Youfang Hu; Zhenying Qin; Yan Zhao; Zi Yang; Yinfang Li; Guanyu Liang; Heyun Lv; Hong Hong; Yuan Song; Yarong Wei; Hongni Yue; Wen Zheng; Guoqin Liu; Yufei Ni; Mei Zhu; Aiping Wu; Juhua Yan; Chenbo Ji; Xirong Guo; Juan Wen; Rui Qin
Journal:  Oncotarget       Date:  2016-12-06
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.