| Literature DB >> 176469 |
Abstract
Fv-1 gene-mediated host restriction of Friend leukemia virus replication was investigated in terms of coat protein synthesis. By using the assay of pseudotype formation with vesicular stomatitis virus. it was shown that under restricting growth conditions the availablity of leukemia virus coat protein for pseudotype formation was decreased. These studies appear to eliminate a pure assembly defect as the mechanism of Fv-1 host restriction.Entities:
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Year: 1976 PMID: 176469 PMCID: PMC515557
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103