Literature DB >> 17645726

Establishment of a new cell line of endometrioid carcinoma of the ovary and its chemosensitivity.

Tomokazu Umezu1, Hiroaki Kajiyama, Mikio Terauchi, Kiyosumi Shibata, Kazuhiko Ino, Akihiro Nawa, Fumitaka Kikkawa.   

Abstract

A new cell line (NOE) of human ovarian endometrioid carcinoma was established and characterized. The cell line showed a short spindle-shaped morphology and continued to grow for more than 4 months without contact inhibition. The doubling time was approximately 15.5 h at the 10th passage. The chromosome number was aneuploid. The IC50 values of paclitaxel, cisplatin and carboplatin were 26.4 ng/mL, 2.4 microg/mL and 32.5 microg/mL, respectively. The NOE cells expressed estrogen receptor alpha. In nude mice, we confirmed tumor formation of NOE cells. These results indicated that NOE cells showed similar chemosensitivity and properties to those of the original tumor and might be useful in basic studies on the diagnosis, treatment and etiology of ovarian tumors.

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Year:  2007        PMID： 17645726     DOI： 10.1111/j.1749-0774.2007.00030.x

Source DB:  PubMed          Journal:  Hum Cell        ISSN： 0914-7470            Impact factor:   4.174


  15 in total

1.  Establishment and characterization of the RMG-V cell line from human ovarian clear cell adenocarcinoma.

Authors:  Daisuke Aoki; Nao Suzuki; Nobuyuki Susumu; Tomomi Noda; Atsushi Suzuki; Yutaka Tamada; Atsushi Higashiguchi; Shinji Oie; Shiro Nozawa
Journal:  Hum Cell       Date:  2005-09       Impact factor: 4.174

2.  Function of estrogen receptor isoforms alpha and beta in endometrial carcinoma cells.

Authors:  Y Zhang; Q Liao; C Chen; L Yu; J Zhao
Journal:  Int J Gynecol Cancer       Date:  2006 Jul-Aug       Impact factor: 3.437

3.  Estrogen and progesterone receptors in epithelial ovarian tumours.

Authors:  K Glavind; A Grove
Journal:  APMIS       Date:  1990-10       Impact factor: 3.205

4.  Establishment and characterization of a cell line (OMC-3) originating from a human mucinous cystadenocarcinoma of the ovary.

Authors:  T Yamada; M Ueda; Y Otsuki; M Ueki; O Sugimoto
Journal:  Gynecol Oncol       Date:  1991-02       Impact factor: 5.482

5.  Establishment and characterization of a human ovarian neoplastic cell line, DO-s.

Authors:  T W Briers; P Stroobants; T M Vandeputte; E J Nouwen; M V Conraads; G Eestermans; D Van Bockstaele; M E De Broe
Journal:  Cancer Res       Date:  1989-09-15       Impact factor: 12.701

6.  Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo.

Authors:  Mikio Terauchi; Hiroaki Kajiyama; Kiyosumi Shibata; Kazuhiko Ino; Shigehiko Mizutani; Fumitaka Kikkawa
Journal:  Oncology       Date:  2005-08-12       Impact factor: 2.935

7.  Inhibition of endometrial carcinoma cell growth using antisense estrogen receptor oligodeoxyribonucleotides.

Authors:  Anthony H Taylor; Farook al-Azzawi; J Howard Pringle; Stephen C Bell
Journal:  Anticancer Res       Date:  2002 Nov-Dec       Impact factor: 2.480

8.  Five-year survival in patients with endometrioid carcinoma of the ovary versus those with serous carcinoma.

Authors:  J Zwart; J P Geisler; H E Geisler
Journal:  Eur J Gynaecol Oncol       Date:  1998       Impact factor: 0.196

9.  Acceleration of invasive activity via matrix metalloproteinases by transfection of the estrogen receptor-alpha gene in endometrial carcinoma cells.

Authors:  Hisanobu Mizumoto; Tsuyoshi Saito; Koji Ashihara; Makoto Nishimura; Ryoichi Tanaka; Ryuichi Kudo
Journal:  Int J Cancer       Date:  2002-08-01       Impact factor: 7.396

10.  Endometrioid carcinoma of the ovary: a retrospective analysis of 106 cases.

Authors:  G Grosso; F Raspagliesi; G Baiocchi; E Di Re; M Colavita; L Cobellis
Journal:  Tumori       Date:  1998 Sep-Oct
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  5 in total

1.  Synchronous endometrioid endometrial and ovarian cancer in a 34-year-old woman.

Authors:  Patrícia Isidro Amaral; Abel Silva; Abílio Lacerda; Carlos Barros
Journal:  BMJ Case Rep       Date:  2015-09-08

2.  HOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells.

Authors:  Hong Yuan; Hiroaki Kajiyama; Satoko Ito; Dan Chen; Kiyosumi Shibata; Michinari Hamaguchi; Fumitaka Kikkawa; Takeshi Senga
Journal:  Oncotarget       Date:  2015-05-30

3.  Microphthalmia-Associated Transcription Factor-Dependent Melanoma Cell Adhesion Molecule Activation Promotes Peritoneal Metastasis of Ovarian Cancer.

Authors:  Kazuhisa Kitami; Masato Yoshihara; Yoshihiro Koya; Mai Sugiyama; Shohei Iyoshi; Kaname Uno; Kazumasa Mogi; Sho Tano; Hiroki Fujimoto; Akihiro Nawa; Fumitaka Kikkawa; Hiroaki Kajiyama
Journal:  Int J Mol Sci       Date:  2020-12-21       Impact factor: 5.923

4.  Establishment and characterization of a cell line (NOMH-1) originating from a human endometrioid adenocarcinoma of the ovary.

Authors:  Takashi Yamada; Takayoshi Kanda; Hiroshi Mori; Kaname Shimokawa; Mitsuo Kagawa; Yuro Shibayama
Journal:  J Ovarian Res       Date:  2013-02-04       Impact factor: 4.234

5.  Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells.

Authors:  Yoshihiro Koya; Wenting Liu; Yoshihiko Yamakita; Takeshi Senga; Kiyosumi Shibata; Mamoru Yamashita; Akihiro Nawa; Fumitaka Kikkawa; Hiroaki Kajiyama
Journal:  Oncotarget       Date:  2018-08-24
  5 in total

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