Literature DB >> 17645606

Chronic orchialgia: consider gabapentin or nortriptyline before considering surgery.

Andrew M Sinclair1, Barry Miller, Ling K Lee.   

Abstract

OBJECTIVE: To establish if there is a role for gabapentin or nortriptyline in the treatment of chronic orchialgia.
METHODS: Twenty-six consecutive patients with chronic orchialgia were seen in the chronic pain clinic by a multidisciplinary team. A pain questionnaire was completed prior to commencing either gabapentin or nortriptyline. They were reviewed at 3 months and a repeat questionnaire completed. A 50% improvement in pain was considered successful.
RESULTS: Complete data was available for 19 patients. Overall, 61.5% of patients commenced on gabapentin and 66.6% of patients commenced on nortriptyline had a greater than 50% improvement in pain. Patients with post-vasectomy testicular pain were considered as a subgroup. None of these patients had a greater than 50% improvement in pain. However, 80% of patients in the subgroup with idiopathic chronic orchialgia had a greater than 50% improvement in pain.
CONCLUSION: Although this is a small study, it appears that gabapentin and nortriptyline are effective in the treatment of idiopathic chronic orchialgia but not post-vasectomy pain.

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Year:  2007        PMID: 17645606     DOI: 10.1111/j.1442-2042.2007.01745.x

Source DB:  PubMed          Journal:  Int J Urol        ISSN: 0919-8172            Impact factor:   3.369


  16 in total

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4.  Prevalence of Relative Deficiencies in Testosterone and Vitamin B12 Among Patients Referred for Chronic Orchialgia: Implications for Management.

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Review 5.  Chronic Scrotal Content Pain: a Review of the Literature and Management Schemes.

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6.  Canadian Urological Association best practice report on chronic scrotal pain.

Authors:  Keith A Jarvi; Christopher Wu; J Curtis Nickel; Trustin Domes; John Grantmyre; Armand Zini
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Review 7.  Scrotal pain: evaluation and management.

Authors:  Chirag G Gordhan; Hossein Sadeghi-Nejad
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8.  Chronic orchialgia: evaluation and discussion of treatment options.

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9.  Relationship between chronic testicular pain and mental health diagnoses.

Authors:  Kuwong B Mwamukonda; Jeremy C Kelley; Doug S Cho; Anna Smitherman
Journal:  Transl Androl Urol       Date:  2019-03

Review 10.  Gold Standard Care of Chronic Scrotal Pain.

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