Literature DB >> 17643936

Susceptibility of naïve and subsets of memory T cells to apoptosis via multiple signaling pathways.

Sudhir Gupta1, Sastry Gollapudi.   

Abstract

Apoptosis is mediated via death receptor, the mitochondrial, and the endoplasmic reticulum pathway. Following activation of naïve T cells with antigens, different subsets of memory T cells are generated. In this review we have discussed relative sensitivity/resistance of naïve and different subsets of memory T cells to apoptosis via different signaling pathways. Molecular basis for differential sensitivity to apoptosis is discussed.

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Year:  2007        PMID： 17643936     DOI： 10.1016/j.autrev.2007.02.005

Source DB:  PubMed          Journal:  Autoimmun Rev        ISSN： 1568-9972            Impact factor:   9.754


  10 in total

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10.  Molecular changes associated with increased TNF-α-induced apoptotis in naïve (TN) and central memory (TCM) CD8+ T cells in aged humans.

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Journal:  Immun Ageing       Date:  2018-01-19       Impact factor: 6.400
  10 in total

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