| Literature DB >> 17643865 |
M S Youssouf1, P Kaiser, M Tahir, G D Singh, S Singh, V K Sharma, N K Satti, S E Haque, R K Johri.
Abstract
The Euphorbia hirta ethanolic extract (EH A001) was found to possess a prominent anti-anaphylactic activity. A preventive effect of EH-A001 given by oral route at dose from 100 to 1000 mg/kg was observed against compound 48/80-induced systemic anaphylaxis. At the same range of dose, EH-A001 inhibited passive cutaneous anaphylaxis (PCA) in rat and active paw anaphylaxis in mice. A suppressive effect of EH-A001 was observed on the release of TNF-alpha and IL-6 from anti-DNP-HSA activated rat peritoneal mast cells.Entities:
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Year: 2007 PMID： 17643865 DOI： 10.1016/j.fitote.2007.06.003
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882