| Literature DB >> 176435 |
K Tabuchi, J M Lehman, W M Kirsch.
Abstract
T antigen was localized in simian virus 40 lytically infected and transformed cells by Fab' antibody conjugates at the ultrastructural level. This virus-specific protein appeared in the cytoplasm of permissive cells as early as 3 h after infection. At later time intervals, the T antigen was localized in both the cytoplasm and nucleus and finally (24 h) in the nucleus. These results suggest a synthesis of T antigen on cytoplasmic ribosomes, with subsequent transfer to the nucleus.Entities:
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Year: 1976 PMID： 176435 PMCID： PMC515456
Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103