Systemic sclerosis treated with dexamethasone pulse.

A 52-year-old women had systemic sclerosis of 8 years duration. The disease was progressive inspite of all available methods of treatment. Treatment with 100 mg dexamethasone given intravenously in 500 ml of 5% glucose on 3 consecutive days every month led to remarkable reversal of all the clinical manifestations over a period of 21 months.