Literature DB >> 1764243

The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.

S Thor1, J Ericson, T Brännström, T Edlund.   

Abstract

We have used immunocytochemical methods to localize the homeodomain LIM protein Isl-1 in the adult rat. Isl-1 immunoreactivity is expressed in polypeptide hormone-producing cells of the endocrine system, in neurons of the peripheral nervous system, and in a subset of brain nuclei. Isl-1 is also expressed in a subset of motoneurons in the spinal cord and brain stem, but not in regions of the central nervous system involved in sensory function or in neocortical areas. The pattern of expression of Isl-1 suggests that this gene may be involved in the specification and maintenance of differentiated phenotypical properties of these cells.

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Year:  1991        PMID： 1764243     DOI： 10.1016/0896-6273(91)90334-v

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  82 in total

1.  Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus.

Authors:  Y Nakagawa; D D O'Leary
Journal:  J Neurosci       Date:  2001-04-15       Impact factor: 6.167

2.  The Dictyostelium LIM domain-containing protein LIM2 is essential for proper chemotaxis and morphogenesis.

Authors:  S Chien; C Y Chung; S Sukumaran; N Osborne; S Lee; C Ellsworth; J G McNally; R A Firtel
Journal:  Mol Biol Cell       Date:  2000-04       Impact factor: 4.138

3.  X-ngnr-1 and Xath3 promote ectopic expression of sensory neuron markers in the neurula ectoderm and have distinct inducing properties in the retina.

Authors:  M Perron; K Opdecamp; K Butler; W A Harris; E J Bellefroid
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

4.  Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription.

Authors:  B Ritz-Laser; B R Gauthier; A Estreicher; A Mamin; T Brun; F Ris; P Salmon; P A Halban; D Trono; J Philippe
Journal:  Diabetologia       Date:  2003-06-03       Impact factor: 10.122

5.  Neurogenin3 triggers beta-cell differentiation of retinoic acid-derived endoderm cells.

Authors:  Amedeo Vetere; Eleonora Marsich; Matteo Di Piazza; Raffaella Koncan; Fulvio Micali; Sergio Paoletti
Journal:  Biochem J       Date:  2003-05-01       Impact factor: 3.857

6.  Specification of the retinal fate of mouse embryonic stem cells by ectopic expression of Rx/rax, a homeobox gene.

Authors:  Yoko Tabata; Yasuo Ouchi; Haruyuki Kamiya; Toshiya Manabe; Ken-ichi Arai; Sumiko Watanabe
Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272

7.  Striatal neuron differentiation from neurosphere-expanded progenitors depends on Gsh2 expression.

Authors:  Josephine B Jensen; Anders Björklund; Malin Parmar
Journal:  J Neurosci       Date:  2004-08-04       Impact factor: 6.167

8.  The LIM-homeodomain protein Isl-1 segregates with somatostatin but not with gastrin expression during differentiation of somatostatin/gastrin precursor cells.

Authors:  L I Larsson; J E Tingstedt; O D Madsen; P Serup; D M Hougaard
Journal:  Endocrine       Date:  1995-07       Impact factor: 3.633

9.  Elevation of transcription factor Islet-1 levels in vivo increases β-cell function but not β-cell mass.

Authors:  Jingxuan Liu; Erik R Walp; Catherine Lee May
Journal:  Islets       Date:  2012-05-01       Impact factor: 2.694

10.  Lineage specification of neuronal precursors in the mouse spinal cord.

Authors:  L J Richards; M Murphy; R Dutton; T J Kilpatrick; A C Puche; B Key; S S Tan; P S Talman; P F Bartlett
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205
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