Literature DB >> 1764055

Effect of erythroid differentiation factor on megakaryocytic differentiation of L8057, a murine megakaryoblastic leukemia cell line.

M Nishimura1, K Kaku, Y Azuno, K Okafuji, Y Etoh, M Shiozaki, H Sasaki, T Inoue, T Kaneko.   

Abstract

To assess the potent effect of erythroid differentiation factor (EDF) on megakaryocytopoiesis, effect of EDF on megakaryocytic differentiation of L8057, a murine megakaryoblastic cell line, was examined. EDF potentiated AchE induction of L8057 in a dose dependent manner. The potency of EDF on megakaryocytic differentiation is comparable to that on erythroid differentiation reported previously. The present results suggest that EDF may play a regulatory role in megakaryocytopoiesis as well as in erythropoiesis.

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Year:  1991        PMID： 1764055     DOI： 10.1016/0006-291x(91)92042-i

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

1.  Integrated Biophysical and Biochemical Signals Augment Megakaryopoiesis and Thrombopoiesis in a Three-Dimensional Rotary Culture System.

Authors:  Yiqing Yang; CuiCui Liu; Xiaohua Lei; Hongtao Wang; Pei Su; Yongxin Ru; Xinhua Ruan; Enkui Duan; Sizhou Feng; Mingzhe Han; Yuanfu Xu; Lihong Shi; Erlie Jiang; Jiaxi Zhou
Journal:  Stem Cells Transl Med       Date:  2015-12-23       Impact factor: 6.940

2.  Conversion of amylase-secreting rat pancreatic AR42J cells to neuronlike cells by activin A.

Authors:  H Ohnishi; N Ohgushi; S Tanaka; H Mogami; R Nobusawa; H Mashima; M Furukawa; T Mine; O Shimada; H Ishikawa
Journal:  J Clin Invest       Date:  1995-05       Impact factor: 14.808

3.  Expression of immunoreactive activin A protein in remodeling lesions associated with interstitial pulmonary fibrosis.

Authors:  T Matsuse; A Ikegami; E Ohga; T Hosoi; T Oka; K Kida; M Fukayama; S Inoue; T Nagase; Y Ouchi; Y Fukuchi
Journal:  Am J Pathol       Date:  1996-03       Impact factor: 4.307

4.  Effects of inhibin on activin A-Induced glucose metabolism in rat hepatocytes.

Authors:  T Mine; H Yasuda; T Fujita; Y Hasegawa
Journal:  Endocrine       Date:  1996-08       Impact factor: 3.633

5.  Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis.

Authors:  N Ohnishi; T Miyata; H Ohnishi; H Yasuda; K Tamada; N Ueda; H Mashima; K Sugano
Journal:  Gut       Date:  2003-10       Impact factor: 23.059

6.  Activin A: an autocrine inhibitor of initiation of DNA synthesis in rat hepatocytes.

Authors:  H Yasuda; T Mine; H Shibata; Y Eto; Y Hasegawa; T Takeuchi; S Asano; I Kojima
Journal:  J Clin Invest       Date:  1993-09       Impact factor: 14.808
  6 in total

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