Literature DB >> 17637353

Mitotic motors: kinesin-5 takes a brake.

Gul Civelekoglu-Scholey1, Jonathan M Scholey.   

Abstract

A kinesin-5-dependent 'sliding filament' mechanism is commonly used to actively push apart the poles during mitotic spindle assembly and elongation, but a recent study now shows that, in C. elegans, kinesin-5 is deployed as a brake to slow down spindle-pole separation.

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Year:  2007        PMID： 17637353     DOI： 10.1016/j.cub.2007.05.030

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  10 in total

Review 1.  Mitosis.

Authors:  J Richard McIntosh
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-09-01       Impact factor: 10.005

2.  Kinesin-5 in Drosophila embryo mitosis: sliding filament or spindle matrix mechanism?

Authors:  Jonathan M Scholey
Journal:  Cell Motil Cytoskeleton       Date:  2009-08

3.  The homotetrameric kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations.

Authors:  Siet M J L van den Wildenberg; Li Tao; Lukas C Kapitein; Christoph F Schmidt; Jonathan M Scholey; Erwin J G Peterman
Journal:  Curr Biol       Date:  2008-12-09       Impact factor: 10.834

4.  Probing the mechanical architecture of the vertebrate meiotic spindle.

Authors:  Takeshi Itabashi; Jun Takagi; Yuta Shimamoto; Hiroaki Onoe; Kenta Kuwana; Isao Shimoyama; Jedidiah Gaetz; Tarun M Kapoor; Shin'ichi Ishiwata
Journal:  Nat Methods       Date:  2009-01-18       Impact factor: 28.547

5.  Kinesin-5-dependent poleward flux and spindle length control in Drosophila embryo mitosis.

Authors:  Ingrid Brust-Mascher; Patrizia Sommi; Dhanya K Cheerambathur; Jonathan M Scholey
Journal:  Mol Biol Cell       Date:  2009-01-21       Impact factor: 4.138

6.  Chromosome passenger complexes control anaphase duration and spindle elongation via a kinesin-5 brake.

Authors:  Daniel K Rozelle; Scott D Hansen; Kenneth B Kaplan
Journal:  J Cell Biol       Date:  2011-04-11       Impact factor: 10.539

7.  Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states.

Authors:  Dhanya K Cheerambathur; Ingrid Brust-Mascher; Gul Civelekoglu-Scholey; Jonathan M Scholey
Journal:  J Cell Biol       Date:  2008-08-04       Impact factor: 10.539

8.  Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16.

Authors:  Hong Qian; Xiangru Xu; Laura E Niklason
Journal:  Oncotarget       Date:  2015-08-07

9.  Prometaphase spindle maintenance by an antagonistic motor-dependent force balance made robust by a disassembling lamin-B envelope.

Authors:  Gul Civelekoglu-Scholey; Li Tao; Ingrid Brust-Mascher; Roy Wollman; Jonathan M Scholey
Journal:  J Cell Biol       Date:  2010-01-11       Impact factor: 10.539

Review 10.  Mechanisms by Which Kinesin-5 Motors Perform Their Multiple Intracellular Functions.

Authors:  Himanshu Pandey; Mary Popov; Alina Goldstein-Levitin; Larisa Gheber
Journal:  Int J Mol Sci       Date:  2021-06-15       Impact factor: 5.923
  10 in total

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