Literature DB >> 17636923

New insight into the mechanism of action of and resistance to isoniazid: interaction of Mycobacterium tuberculosis enoyl-ACP reductase with INH-NADP.

Argyrides Argyrou1, Matthew W Vetting, John S Blanchard.   

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Year:  2007        PMID： 17636923      PMCID： PMC2525798          DOI： 10.1021/ja073160k

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  13 in total

1.  Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis.

Authors:  Michelle H Larsen; Catherine Vilchèze; Laurent Kremer; Gurdyal S Besra; Linda Parsons; Max Salfinger; Leonid Heifets; Manzour H Hazbon; David Alland; James C Sacchettini; William R Jacobs
Journal:  Mol Microbiol       Date:  2002-10       Impact factor: 3.501

2.  Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid.

Authors:  Argyrides Argyrou; Matthew W Vetting; Bola Aladegbami; John S Blanchard
Journal:  Nat Struct Mol Biol       Date:  2006-04-30       Impact factor: 15.369

3.  Hydrogen peroxide-mediated isoniazid activation catalyzed by Mycobacterium tuberculosis catalase-peroxidase (KatG) and its S315T mutant.

Authors:  Xiangbo Zhao; Hong Yu; Shengwei Yu; Feng Wang; James C Sacchettini; Richard S Magliozzo
Journal:  Biochemistry       Date:  2006-04-04       Impact factor: 3.162

4.  Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis.

Authors:  D A Rozwarski; G A Grant; D H Barton; W R Jacobs; J C Sacchettini
Journal:  Science       Date:  1998-01-02       Impact factor: 47.728

5.  Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis.

Authors:  A Quémard; J C Sacchettini; A Dessen; C Vilcheze; R Bittman; W R Jacobs; J S Blanchard
Journal:  Biochemistry       Date:  1995-07-04       Impact factor: 3.162

6.  inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis.

Authors:  A Banerjee; E Dubnau; A Quemard; V Balasubramanian; K S Um; T Wilson; D Collins; G de Lisle; W R Jacobs
Journal:  Science       Date:  1994-01-14       Impact factor: 47.728

7.  The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis.

Authors:  Y Zhang; B Heym; B Allen; D Young; S Cole
Journal:  Nature       Date:  1992-08-13       Impact factor: 49.962

Review 8.  Tuberculosis: commentary on a reemergent killer.

Authors:  B R Bloom; C J Murray
Journal:  Science       Date:  1992-08-21       Impact factor: 47.728

9.  The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance.

Authors:  Richa Rawat; Adrian Whitty; Peter J Tonge
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-17       Impact factor: 11.205

10.  Mn(III) pyrophosphate as an efficient tool for studying the mode of action of isoniazid on the InhA protein of Mycobacterium tuberculosis.

Authors:  Michel Nguyen; Annaïk Quémard; Sylvain Broussy; Jean Bernadou; Bernard Meunier
Journal:  Antimicrob Agents Chemother       Date:  2002-07       Impact factor: 5.191
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  13 in total

1.  A virtual screen discovers novel, fragment-sized inhibitors of Mycobacterium tuberculosis InhA.

Authors:  Alexander L Perryman; Weixuan Yu; Xin Wang; Sean Ekins; Stefano Forli; Shao-Gang Li; Joel S Freundlich; Peter J Tonge; Arthur J Olson
Journal:  J Chem Inf Model       Date:  2015-02-17       Impact factor: 4.956

2.  Metabolomics of urine for the assessment of microvesicular lipid accumulation in the liver following isoniazid exposure.

Authors:  Susan J Sumner; Jason P Burgess; Rodney W Snyder; James A Popp; Timothy R Fennell
Journal:  Metabolomics       Date:  2010-06-01       Impact factor: 4.290

3.  Rifampin-isoniazid oligonucleotide typing: an alternative format for rapid detection of multidrug-resistant Mycobacterium tuberculosis.

Authors:  Iván Hernández-Neuta; Andrés Varela; Anandi Martin; Andrea von Groll; Pontus Jureen; Beatriz López; Belén Imperiale; Girts Sķenders; Viviana Ritacco; Sven Hoffner; Nora Morcillo; Juan Carlos Palomino; Patricia Del Portillo
Journal:  J Clin Microbiol       Date:  2010-09-29       Impact factor: 5.948

4.  Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.

Authors:  Jing Hou; Heping Zheng; Maksymilian Chruszcz; Matthew D Zimmerman; Igor A Shumilin; Tomasz Osinski; Matt Demas; Sarah Grimshaw; Wladek Minor
Journal:  J Bacteriol       Date:  2015-11-09       Impact factor: 3.490

5.  Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development.

Authors:  Jason W Holder; Jil C Ulrich; Anthony C DeBono; Paul A Godfrey; Christopher A Desjardins; Jeremy Zucker; Qiandong Zeng; Alex L B Leach; Ion Ghiviriga; Christine Dancel; Thomas Abeel; Dirk Gevers; Chinnappa D Kodira; Brian Desany; Jason P Affourtit; Bruce W Birren; Anthony J Sinskey
Journal:  PLoS Genet       Date:  2011-09-08       Impact factor: 5.917

6.  In silico-based high-throughput screen for discovery of novel combinations for tuberculosis treatment.

Authors:  Ragini Singh; Vasanthi Ramachandran; Radha Shandil; Sreevalli Sharma; Swati Khandelwal; Malancha Karmarkar; Naveen Kumar; Suresh Solapure; Ramanatha Saralaya; Robert Nanduri; Vijender Panduga; Jitendar Reddy; K R Prabhakar; Swaminathan Rajagopalan; Narasimha Rao; Shridhar Narayanan; Anand Anandkumar; V Balasubramanian; Santanu Datta
Journal:  Antimicrob Agents Chemother       Date:  2015-07-06       Impact factor: 5.191

7.  Antitubercular pharmacodynamics of phenothiazines.

Authors:  Ashley J Warman; Teresa S Rito; Nicholas E Fisher; Darren M Moss; Neil G Berry; Paul M O'Neill; Stephen A Ward; Giancarlo A Biagini
Journal:  J Antimicrob Chemother       Date:  2012-12-09       Impact factor: 5.790

8.  The binding characteristics of isoniazid with copper-zinc superoxide dismutase and its effect on enzymatic activity.

Authors:  Nana Du; Liangquan Sheng; Zhaodi Liu; Xiaojuan Hu; Huajie Xu; Shuisheng Chen
Journal:  Chem Cent J       Date:  2013-06-06       Impact factor: 4.215

9.  Delineating bacteriostatic and bactericidal targets in mycobacteria using IPTG inducible antisense expression.

Authors:  Parvinder Kaur; Saurabh Agarwal; Santanu Datta
Journal:  PLoS One       Date:  2009-06-15       Impact factor: 3.240

10.  Isoniazid Killing of Mycobacterium smegmatis NADH Pyrophosphatase Mutant at Single-Cell Level using Microfluidics and Time-Lapse Microscopy.

Authors:  Meltem Elitas
Journal:  Sci Rep       Date:  2017-09-07       Impact factor: 4.379
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