Literature DB >> 17634702

Even low-intensity and low-volume exercise training may improve insulin resistance in the elderly.

Satoru Kodama1, Miao Shu, Kazumi Saito, Haruka Murakami, Kiyoji Tanaka, Shinya Kuno, Ryuichi Ajisaka, Yasuko Sone, Fumiko Onitake, Akimitsu Takahashi, Hitoshi Shimano, Kazuo Kondo, Nobuhiro Yamada, Hirohito Sone.   

Abstract

OBJECTIVE: Moderate to high intensity exercise training is known to ameliorate the coronary risk factors in relation to an improvement in body composition. However, the benefit of low-intensity and low-volume training for these risk factors remains unclear in elderly people. Therefore, we investigated the effects of low-intensity and low-volume exercise training on blood lipid values and insulin resistance in the elderly.
METHODS: A total of 56 healthy elderly individuals (42 females and 14 males) aged 64+/-6 years participated in a 12-week exercise program, comprising aerobic training and resistance training.
RESULTS: After the program, there were no significant changes in high-density lipoprotein cholesterol, triglyceride serum levels, or in peak oxygen uptake on average. However, the homeostasis of minimal assessment of insulin resistance (HOMA-IR) value was significantly reduced by 21%. The participants were categorized into tertiles based on initial Body Mass Index (BMI). The Middle-BMI group (non-obese subjects) showed reduced HOMA-IR (2.0-->1.3, P<0.01), but this reduction was not associated with the reduction in BMI (r=0.08, P=0.74), whereas the two reductions were significantly associated in the High-BMI group (r=0.61, P=0.01).
CONCLUSION: Even low-intensity and low-volume exercise training, which would ordinarily be insufficient for improving mean lipid values or aerobic fitness, was found to be effective in improving insulin resistance in the elderly. The improvement in insulin resistance was independent of the improvement in obesity.

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Year:  2007        PMID: 17634702     DOI: 10.2169/internalmedicine.46.0096

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  6 in total

1.  Very short bouts of non-exercise physical activity associated with metabolic syndrome under free-living conditions in Japanese female adults.

Authors:  Makoto Ayabe; Hideaki Kumahara; Kazuhiro Morimura; Kojiro Ishii; Naoki Sakane; Hiroaki Tanaka
Journal:  Eur J Appl Physiol       Date:  2012-02-07       Impact factor: 3.078

2.  Aging, resistance training, and diabetes prevention.

Authors:  Kyle D Flack; Kevin P Davy; Matthew W Hulver; Richard A Winett; Madlyn I Frisard; Brenda M Davy
Journal:  J Aging Res       Date:  2010-12-15

3.  Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.

Authors:  Alex H Cho; Ley A Killeya-Jones; Julianne M O'Daniel; Kensaku Kawamoto; Patrick Gallagher; Susanne Haga; Joseph E Lucas; Gloria M Trujillo; Scott V Joy; Geoffrey S Ginsburg
Journal:  BMC Health Serv Res       Date:  2012-01-18       Impact factor: 2.655

4.  The effect of 8 weeks aerobic exercise on insulin resistance in type 2 diabetes: a randomized clinical trial.

Authors:  Narges Motahari-Tabari; Marjan Ahmad Shirvani; Mahbobeh Shirzad-E-Ahoodashty; Elham Yousefi-Abdolmaleki; Mojgan Teimourzadeh
Journal:  Glob J Health Sci       Date:  2014-08-14

Review 5.  The Effect of Exercise on Glucoregulatory Hormones: A Countermeasure to Human Aging: Insights from a Comprehensive Review of the Literature.

Authors:  Maha Sellami; Nicola Luigi Bragazzi; Maamer Slimani; Lawrence Hayes; Georges Jabbour; Andrea De Giorgio; Benoit Dugué
Journal:  Int J Environ Res Public Health       Date:  2019-05-15       Impact factor: 3.390

6.  Relationship of visfatin level to pancreatic endocrine hormone level, HOMA-IR index, and HOMA β-cell index in overweight women who performed hydraulic resistance exercise.

Authors:  Chang Ho Ha; Brenda Swearingin; Yong Kyun Jeon
Journal:  J Phys Ther Sci       Date:  2015-09-30
  6 in total

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