Literature DB >> 17633991

[Partial nephrectomy for renal cancers larger than 4 cm].

Elie Nemr1, Georges Azar, Fadi Fakih, Edward Chalouhy, Maroun Moukarzel, Pierre Sarkis, Raghid Khoury, Nadim Ayoub, Sleiman Merhej.   

Abstract

OBJECTIVE: To compare the results in patients operated by partial nephrectomy (PN) and radical nephrectomy (RN) for renal cancers < 4 cm, between 4 and 7 cm and > 7 cm.
MATERIALS AND METHODS: Retrospective study including 107 patients operated for renal cancer between 1998 and 2004. Demographic characteristics, TNM stage, tumour diameter and type of surgery (PN vs RN) were recorded. The patients' current status was determined and a survival curve was constructed by the Kaplan-Meier method.
RESULTS: 35.2% patients were operated by PN and 64.8% were operated by RN. The mean follow-up was 45 months. No significant difference in recurrence-free survival rate was observed between patients operated by PN and RN for tumours < 4 cm (93.3% vs 92.3%, respectively, p = 0.243), or for tumours between 4 and 7 cm (100% vs 89.3%, respectively, p = 0.564) or for tumours > 7 cm (100% vs 85.5%, respectively, p = 0.218).
CONCLUSION: Partial nephrectomy is the standard treatment for tumours < 4 cm, but this study suggests that it is just as effective for tumours up to 7 cm in diameter. Although partial nephrectomy also appears to be a safe treatment for tumours > 7 cm, further studies based on a greater number of tumours in this size category with a longer follow-up are necessary.

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Year:  2007        PMID: 17633991     DOI: 10.1016/s1166-7087(07)92297-6

Source DB:  PubMed          Journal:  Prog Urol        ISSN: 1166-7087            Impact factor:   0.915


  3 in total

Review 1.  Open partial nephrectomy: ancient art or currently available technique?

Authors:  Mauro Seveso; Fabio Grizzi; Giorgio Bozzini; Alberto Mandressi; Giorgio Guazzoni; Gianluigi Taverna
Journal:  Int Urol Nephrol       Date:  2015-10-05       Impact factor: 2.370

2.  Comparison of Partial and Radical Nephrectomy for pT1b Renal Cell Carcinoma.

Authors:  Jong Min Kim; Phil Hyun Song; Hyun Tae Kim; Tong Choon Park
Journal:  Korean J Urol       Date:  2010-09-16

3.  Predictors of postoperative renal functional damage after nephron-sparing surgery.

Authors:  Jun Qi; Yongjiang Yu; Tao Huang; Qiang Bai; Jian Kang; Junhao Liang; Yu Wu
Journal:  World J Surg Oncol       Date:  2013-08-29       Impact factor: 2.754

  3 in total

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