Literature DB >> 17633789

Lapatinib.

Beverly Moy, Peter Kirkpatrick, Santwana Kar, Paul Goss.   

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Year:  2007        PMID: 17633789     DOI: 10.1038/nrd2332

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  46 in total

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2.  Evaluation of lapatinib and topotecan combination therapy: tissue culture, murine xenograft, and phase I clinical trial data.

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Review 3.  Nuclear mode of the EGFR signaling network: biology, prognostic value, and therapeutic implications.

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Review 4.  Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations.

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6.  From bench to bedside: the growing use of translational research in cancer medicine.

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7.  Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib.

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8.  Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells.

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Review 9.  Human epidermal growth factor receptor dimerization analysis in breast cancer diagnosis: potential for improving testing accuracy and treatment selection.

Authors:  Melanie Spears; John M S Bartlett
Journal:  Mol Diagn Ther       Date:  2009-12-01       Impact factor: 4.074

10.  The HER2- and heregulin β1 (HRG)-inducible TNFR superfamily member Fn14 promotes HRG-driven breast cancer cell migration, invasion, and MMP9 expression.

Authors:  Kaushal Asrani; Ruth A Keri; Rebeca Galisteo; Sharron A N Brown; Sarah J Morgan; Arundhati Ghosh; Nhan L Tran; Jeffrey A Winkles
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