Literature DB >> 1763185

Isosterism and bioisosterism in drug design.

A Burger1.   

Abstract

Mesh：

Year:  1991        PMID： 1763185     DOI： 10.1007/978-3-0348-7139-6_7

Source DB:  PubMed          Journal:  Prog Drug Res        ISSN： 0071-786X


× No keyword cloud information.
  21 in total

1.  Proteins with beta-(thienopyrrolyl)alanines as alternative chromophores and pharmaceutically active amino acids.

Authors:  N Budisa; S Alefelder; J H Bae; R Golbik; C Minks; R Huber; L Moroder
Journal:  Protein Sci       Date:  2001-07       Impact factor: 6.725

2.  Identification of target-specific bioisosteric fragments from ligand-protein crystallographic data.

Authors:  Elizabeth A Kennewell; Peter Willett; Pierre Ducrot; Claude Luttmann
Journal:  J Comput Aided Mol Des       Date:  2006-10-13       Impact factor: 3.686

3.  1,4-Thienodiazepine-2,5-diones via MCR (II): scaffold hopping by Gewald and Ugi-deprotection-cyclization strategy.

Authors:  Yijun Huang; Alexander Dömling
Journal:  Chem Biol Drug Des       Date:  2010-06-09       Impact factor: 2.817

4.  One-pot synthesis, biological evaluation, and docking study of new chromeno-annulated thiopyrano[2,3-c]pyrazoles.

Authors:  Bhagyashri D Parmar; Tushar R Sutariya; Gaurangkumar C Brahmbhatt; Narsidas J Parmar; Rajni Kant; Vivek K Gupta; Prashant R Murumkar; Mayank Kumar Sharma; Mange Ram Yadav
Journal:  Mol Divers       Date:  2016-03-26       Impact factor: 2.943

5.  GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile.

Authors:  Elisia Villemure; Matthew Volgraf; Yu Jiang; Guosheng Wu; Cuong Q Ly; Po-Wai Yuen; Aijun Lu; Xifeng Luo; Mingcui Liu; Shun Zhang; Patrick J Lupardus; Heidi J A Wallweber; Bianca M Liederer; Gauri Deshmukh; Emile Plise; Suzanne Tay; Tzu-Ming Wang; Jesse E Hanson; David H Hackos; Kimberly Scearce-Levie; Jacob B Schwarz; Benjamin D Sellers
Journal:  ACS Med Chem Lett       Date:  2016-10-31       Impact factor: 4.345

6.  Identification of a potential lead structure for designing new antimicrobials to treat infections caused by Staphylococcus epidermidis-resistant strains.

Authors:  Luiz C S Pinheiro; Paula A Abreu; Ilidio F Afonso; Bruno Leal; Luiz C D Corrêa; Júlio C Borges; Isakelly P Marques; André L Lourenço; Plinio Sathler; Andre L dos Santos; Cid A Medeiros; Lúcio M Cabral; Maurício L O Júnior; Gilberto A Romeiro; Vitor F Ferreira; Carlos R Rodrigues; Helena C Castro; Alice M R Bernardino
Journal:  Curr Microbiol       Date:  2008-09-23       Impact factor: 2.188

7.  N-(Cyano-meth-yl)benzamide.

Authors:  Younas Aouine; Anouar Alami; Abdelilah El Hallaoui; Abdelrhani Elachqar; Hafid Zouihri
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-02-06

Review 8.  Privileged diazepine compounds and their emergence as bromodomain inhibitors.

Authors:  Steven G Smith; Roberto Sanchez; Ming-Ming Zhou
Journal:  Chem Biol       Date:  2014-04-17

9.  Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function. A computational study on gamma-aminobutyric acid (GABA) related compounds.

Authors:  Paolo Tosco; Marco L Lolli
Journal:  J Mol Model       Date:  2008-02-05       Impact factor: 1.810

10.  Improved Synthesis of Anxiolytic, Anticonvulsant and Antinociceptive α2/α3-GABA(A)ergic Receptor Subtype Selective Ligands as Promising Agents to Treat Anxiety, Epilepsy, as well as Neuropathic Pain.

Authors:  Guanguan Li; Lalit K Golani; Rajwana Jahan; Farjana Rashid; James M Cook
Journal:  Synthesis (Stuttg)       Date:  2018-10       Impact factor: 3.157
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.