Nickel(II) thiohydrazide and thiodiamine complexes: synthesis, characterization, antibacterial, antifungal and thermal studies.

Nickel(II) complexes of type [Ni(L)(2)Cl(2)] and [Ni(L)(2)(OCOCH(3))(2)], where L=N,N-diphenyl-N-thiohydrazide (L(1)) and (N,N-diphenyl-N-thio)-1,3-propanediamine (L(2)), have been synthesized. The thiodiamines coordinate as a bidentate N-S ligand. The synthesized nickel(II) complexes of the thiodiamines were characterized by elemental analysis, IR, mass, electronic and (1)H NMR spectroscopic and TG/DTA studies. Various kinetic and thermodynamic parameters like order of reaction (n), activation energy (E(a)), apparent activation entropy (S(#)) and heat of reaction (DeltaH) have also been carried out for one complex. These complexes were also screened for in vitro antifungal and in vitro antibacterial activities and significant activity have been found.