Literature DB >> 17628033

Synthesis, analgesic and anti-inflammatory activity of 4-(2-phenoxyphenyl)semicarbazones.

Ardeshir Rineh1, Nosratollah Mahmoodi, Mohammad Abdollahi, Alireza Foroumadi, Maedeh Sorkhi, Abbas Shafiee.   

Abstract

A series of 4-(2-phenoxyphenyl)semicarbazones was synthesized and evaluated for their analgesic and anti-inflammatory activities. Several compounds (e. g. 10h, 10i, and 11i) were found to be more potent than the reference drug mefenamic acid in the formalin test. Based on the results of an anti-inflammatory study, 1-(1-(2,5-dimethoxyphenyl)ethylidene)-4-(2-phenoxyphenyl)semicarbazide 11i was the most active compound.

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Year:  2007        PMID： 17628033     DOI： 10.1002/ardp.200700045

Source DB:  PubMed          Journal:  Arch Pharm (Weinheim)        ISSN： 0365-6233            Impact factor:   3.751


  3 in total

1.  Novel platinum(II) and palladium(II) complexes of thiosemicarbazones derived from 5-substitutedthiophene-2-carboxaldehydes and their antiviral and cytotoxic activities.

Authors:  Ayşegül Karaküçük-İyidoğan; Demet Taşdemir; Emine Elçin Oruç-Emre; Jan Balzarini
Journal:  Eur J Med Chem       Date:  2011-10-01       Impact factor: 6.514

2.  Synthesis of Two Novel 3-Amino-5-[4-chloro-2-phenoxyphenyl]-4H-1,2,4-triazoles with Anticonvulsant Activity.

Authors:  Mohammad Mahdavi; Tahmineh Akbarzadeh; Vahid Sheibani; Maryam Abbasi; Loghman Firoozpour; Sayyed Abbas Tabatabai; Abbas Shafiee; Alireza Foroumadi
Journal:  Iran J Pharm Res       Date:  2010       Impact factor: 1.696

3.  Synthesis and analgesic activity of novel hydrazide and hydrazine derivatives.

Authors:  Mansur Nassiri Koopaei; Mohammad Javad Assarzadeh; Ali Almasirad; Seyedeh Farnaz Ghasemi-Niri; Mohsen Amini; Abbas Kebriaeezadeh; Nasser Nassiri Koopaei; Maryam Ghadimi; Arash Tabei
Journal:  Iran J Pharm Res       Date:  2013       Impact factor: 1.696
  3 in total

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