Literature DB >> 17627594

Chimeric T helper-B cell peptides induce protective response against Japanese encephalitis virus in mice.

Shailesh Shyam Dewasthaly1, Gauri Sanjay Bhonde, Vasudha Shankarraman, S Moanaro Biswas, Vijay Madhukar Ayachit, Milind Madhukar Gore.   

Abstract

Virus neutralizing MAb binding and T helper cell stimulating peptide epitopes from structural and non-structural proteins of Japanese encephalitis virus were delineated. It was observed that priming by T helper peptides potentiated neutralizing antibody response against JE virus. Immunization with chimeric T helper - B cell peptides could thus protect mice from lethal challenge with JE virus.

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Year:  2007        PMID： 17627594     DOI： 10.2174/092986607780990028

Source DB:  PubMed          Journal:  Protein Pept Lett        ISSN： 0929-8665            Impact factor:   1.890


  4 in total

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Authors:  Mohammad Feraz Ahsan; Milind M Gore
Journal:  Virol J       Date:  2011-08-02       Impact factor: 4.099
  4 in total

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