Literature DB >> 17624986

Bevacizumab demonstrates activity in advanced refractory fallopian tube carcinoma.

N Arora1, D Tewari, C Cowan, B Saffari, B J Monk, R A Burger.   

Abstract

The targeting of angiogenesis pathways in the treatment of gynecological cancers is an exciting development in cancer therapy. Bevacizumab has been shown to have activity in ovarian cancer through its inhibition of the vascular endothelial growth factor. Fallopian tube carcinoma is a rare malignancy and is often treated in a similar manner as ovarian carcinoma. We present a case of a complete response in a woman with refractory metastatic fallopian tube carcinoma treated with bevacizumab. This report demonstrates the significance of anti-angiogenesis therapy in the treatment of these tumors.

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Year:  2007        PMID: 17624986     DOI: 10.1111/j.1525-1438.2007.01026.x

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  3 in total

Review 1.  Complete remission of ovarian cancer induced intractable malignant ascites with intraperitoneal bevacizumab. Immunological observations and a literature review.

Authors:  Filippo Bellati; Chiara Napoletano; Ilary Ruscito; Maria Pastore; Milena Pernice; Morena Antonilli; Marianna Nuti; Pierluigi Benedetti Panici
Journal:  Invest New Drugs       Date:  2009-11-24       Impact factor: 3.850

Review 2.  Monoclonal antibodies in gynecological cancer: a critical point of view.

Authors:  Filippo Bellati; Chiara Napoletano; Maria Luisa Gasparri; Valeria Visconti; Ilaria Grazia Zizzari; Ilary Ruscito; Jlenia Caccetta; Aurelia Rughetti; Pierluigi Benedetti-Panici; Marianna Nuti
Journal:  Clin Dev Immunol       Date:  2011-12-26

3.  Randomized Trial of Intravenous Versus Intraperitoneal Chemotherapy Plus Bevacizumab in Advanced Ovarian Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study.

Authors:  Joan L Walker; Mark F Brady; Lari Wenzel; Gini F Fleming; Helen Q Huang; Paul A DiSilvestro; Keiichi Fujiwara; David S Alberts; Wenxin Zheng; Krishnansu S Tewari; David E Cohn; Matthew A Powell; Linda Van Le; Susan A Davidson; Heidi J Gray; Peter G Rose; Carol Aghajanian; Tashanna Myers; Angeles Alvarez Secord; Stephen C Rubin; Robert S Mannel
Journal:  J Clin Oncol       Date:  2019-04-19       Impact factor: 50.717

  3 in total

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