Literature DB >> 17624387

Steady state of homozygosity and Gst for the island model.

Sivan Rottenstreich1, Judith R Miller, Matthew B Hamilton.   

Abstract

We examine homozygosity and G(st) for a subdivided population governed by the finite island model. Assuming an infinite allele model and strong mutation we show that the steady state distributions of G(st) and homozygosity have asymptotic expansions in the mutation rate. We use this observation to derive asymptotic expansions for various moments of homozygosity and to derive rigorous formulas for the mean and variance of G(st). We show that G(st) approximately 1/(1+2Nm), similarly to the well known formula of Wright for the infinite island model, and that the variance of G(st) goes to zero as mutation increases.

Mesh:

Year:  2007        PMID: 17624387     DOI: 10.1016/j.tpb.2007.06.001

Source DB:  PubMed          Journal:  Theor Popul Biol        ISSN: 0040-5809            Impact factor:   1.570


  2 in total

1.  Quasi equilibrium, variance effective size and fixation index for populations with substructure.

Authors:  Ola Hössjer; Nils Ryman
Journal:  J Math Biol       Date:  2013-10-15       Impact factor: 2.259

2.  The distribution of Fst and other genetic statistics for a class of population structure models.

Authors:  Sivan Leviyang
Journal:  J Math Biol       Date:  2010-02-26       Impact factor: 2.259

  2 in total

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