Literature DB >> 17623703

HMMoC--a compiler for hidden Markov models.

Gerton Lunter1.   

Abstract

UNLABELLED: Hidden Markov models are widely applied within computational biology. The large data sets and complex models involved demand optimized implementations, while efficient exploration of model space requires rapid prototyping. These requirements are not met by existing solutions, and hand-coding is time-consuming and error-prone. Here, I present a compiler that takes over the mechanical process of implementing HMM algorithms, by translating high-level XML descriptions into efficient C++ implementations. The compiler is highly customizable, produces efficient and bug-free code, and includes several optimizations. AVAILABILITY: http://genserv.anat.ox.ac.uk/software.

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Year:  2007        PMID: 17623703     DOI: 10.1093/bioinformatics/btm350

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  11 in total

1.  Efficient algorithms for training the parameters of hidden Markov models using stochastic expectation maximization (EM) training and Viterbi training.

Authors:  Tin Y Lam; Irmtraud M Meyer
Journal:  Algorithms Mol Biol       Date:  2010-12-09       Impact factor: 1.405

2.  StochHMM: a flexible hidden Markov model tool and C++ library.

Authors:  Paul C Lott; Ian Korf
Journal:  Bioinformatics       Date:  2014-01-30       Impact factor: 6.937

3.  Developing and applying heterogeneous phylogenetic models with XRate.

Authors:  Oscar Westesson; Ian Holmes
Journal:  PLoS One       Date:  2012-06-05       Impact factor: 3.240

4.  xREI: a phylo-grammar visualization webserver.

Authors:  Lars Barquist; Ian Holmes
Journal:  Nucleic Acids Res       Date:  2008-06-03       Impact factor: 16.971

5.  Consistency of VDJ Rearrangement and Substitution Parameters Enables Accurate B Cell Receptor Sequence Annotation.

Authors:  Duncan K Ralph; Frederick A Matsen
Journal:  PLoS Comput Biol       Date:  2016-01-11       Impact factor: 4.475

6.  Evolutionary triplet models of structured RNA.

Authors:  Robert K Bradley; Ian Holmes
Journal:  PLoS Comput Biol       Date:  2009-08-28       Impact factor: 4.475

7.  HMMCONVERTER 1.0: a toolbox for hidden Markov models.

Authors:  Tin Yin Lam; Irmtraud M Meyer
Journal:  Nucleic Acids Res       Date:  2009-11       Impact factor: 16.971

8.  ToPS: a framework to manipulate probabilistic models of sequence data.

Authors:  André Yoshiaki Kashiwabara; Igor Bonadio; Vitor Onuchic; Felipe Amado; Rafael Mathias; Alan Mitchell Durham
Journal:  PLoS Comput Biol       Date:  2013-10-03       Impact factor: 4.475

9.  Fast statistical alignment.

Authors:  Robert K Bradley; Adam Roberts; Michael Smoot; Sudeep Juvekar; Jaeyoung Do; Colin Dewey; Ian Holmes; Lior Pachter
Journal:  PLoS Comput Biol       Date:  2009-05-29       Impact factor: 4.475

10.  Investigating selection on viruses: a statistical alignment approach.

Authors:  Saskia de Groot; Thomas Mailund; Gerton Lunter; Jotun Hein
Journal:  BMC Bioinformatics       Date:  2008-07-10       Impact factor: 3.169

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