Differentiation of MEG activity in multiple sclerosis patients with the use of nonlinear analysis.

The aim of this study is to investigate if there is any nonlinearity in the magnetoencephalographic recordings of patients with multiple sclerosis in comparison with controls in order to find out the differences in the mechanisms underlying their brain waves. Five multiple sclerosis patients and five controls were included in this study. Chaotic activity of multiple sclerosis patients is lower than in the normal brain. Nonlinear analysis may offer fertile perspectives for understanding the features of patients with multiple sclerosis.