Literature DB >> 17620926

Genes in context: probing the genetics of fracture resistance.

Neil A Sharkey1, Dean H Lang.   

Abstract

Fracture resistance is a complex trait dictated by bone volume, shape, internal architecture, and material performance of the calcified tissue itself, all of which may be influenced by a large number of different genetic and environmental processes. Quantitative Trait Loci analyses provide a sobering picture of this system and illustrate the importance of considering genes in context.

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Year:  2007        PMID： 17620926     DOI： 10.1097/jes.0b013e31809ff2ca

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN： 0091-6331            Impact factor:   6.230


  4 in total

Review 1.  Systems analysis of bone.

Authors:  Karl J Jepsen
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2009 Jul-Aug

2.  A delay in pubertal onset affects the covariation of body weight, estradiol, and bone size.

Authors:  Vanessa R Yingling
Journal:  Calcif Tissue Int       Date:  2009-03-13       Impact factor: 4.333

3.  Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains.

Authors:  Karl J Jepsen; Bin Hu; Steven M Tommasini; Hayden-William Courtland; Christopher Price; Matthew Cordova; Joseph H Nadeau
Journal:  Mamm Genome       Date:  2008-12-05       Impact factor: 2.957

4.  Phenotypic integration among trabecular and cortical bone traits establishes mechanical functionality of inbred mouse vertebrae.

Authors:  Steven M Tommasini; Bin Hu; Joseph H Nadeau; Karl J Jepsen
Journal:  J Bone Miner Res       Date:  2009-04       Impact factor: 6.741
  4 in total

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