| Literature DB >> 17620707 |
Laura-Lee Clancy Kelley1, Bret D Dillard, Wolfram Tempel, Lirong Chen, Neil Shaw, Doowon Lee, M Gary Newton, Frank J Sugar, Francis E Jenney, Han Seung Lee, Claudia Shah, Farris L Poole, Michael W W Adams, Jane S Richardson, David C Richardson, Zhi-Jie Liu, Bi-Cheng Wang, John Rose.
Abstract
The hypothetical protein PF0899 is a 95-residue peptide from the hyperthermophilic archaeon Pyrococcus furiosus that represents a gene family with six members. P. furiosus ORF PF0899 has been cloned, expressed and crystallized and its structure has been determined by the Southeast Collaboratory for Structural Genomics (http://www.secsg.org). The structure was solved using the SCA2Structure pipeline from multiple data sets and has been refined to 1.85 A against the highest resolution data set collected (a presumed gold derivative), with a crystallographic R factor of 21.0% and R(free) of 24.0%. The refined structure shows some structural similarity to a wedge-shaped domain observed in the structure of the major capsid protein from bacteriophage HK97, suggesting that PF0899 may be a structural protein.Entities:
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Year: 2007 PMID： 17620707 PMCID： PMC2335137 DOI： 10.1107/S1744309107024049
Source DB: PubMed Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun ISSN： 1744-3091