Literature DB >> 17618966

The impact of neurotrauma on society: an international perspective.

Peter Reilly1.   

Abstract

Neurotrauma, in many countries and particularly in the younger age group kills more people than AIDS or cancer but unlike these diseases the causes are known and it is preventable. The costs to communities in terms of suffering and economics are enormous. The common causes are road traffic accidents, falls and violence. Neurotrauma affects particularly the developing world where it consumes already over stretched health resources. In the developed world steps to reduce the incidence of neurotrauma and to treat the victims have had some effect nevertheless it stills remains an endemic problem which does not receive the public awareness or the political support it deserves. For the victims there is general agreement on the principles of clinical management but often difficulties in applying early and effective care in countries with the greatest need because of shortage of facilities and expertise. To reduce the overall burden of neurotrauma demands actions which extend from the political to basic patient care. There have been remarkable advances in the understanding of acute brain and spinal cord injury and encouraging possibilities for effective neuroprotection, repair and regeneration but in the broader context prevention of neurotrauma is the urgent imperative. In this endeavour the neuroscientist has knowledge which informs and encourages policy makers to take the steps necessary to reduce injury. These steps require political will and community support for hard decisions which impact on the way people conduct their daily lives. The WHO predicts that unless there are changes in present policies and if there are no additional road safety countermeasures put in place, there will be a major increase in road traffic fatalities over the next 20 years and beyond (World Health Organisation. (2004). www.who.int).

Entities:  

Mesh:

Year:  2007        PMID: 17618966     DOI: 10.1016/S0079-6123(06)61001-7

Source DB:  PubMed          Journal:  Prog Brain Res        ISSN: 0079-6123            Impact factor:   2.453


  29 in total

Review 1.  Global neurotrauma research challenges and opportunities.

Authors:  Andrés M Rubiano; Nancy Carney; Randall Chesnut; Juan Carlos Puyana
Journal:  Nature       Date:  2015-11-19       Impact factor: 49.962

2.  Acute over-the-counter pharmacological intervention does not adversely affect behavioral outcome following diffuse traumatic brain injury in the mouse.

Authors:  Jordan L Harrison; Rachel K Rowe; Bruce F O'Hara; P David Adelson; Jonathan Lifshitz
Journal:  Exp Brain Res       Date:  2014-04-24       Impact factor: 1.972

3.  Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury.

Authors:  L-Y Yang; Y-H Chu; D Tweedie; Q-S Yu; C G Pick; B J Hoffer; N H Greig; J-Y Wang
Journal:  Exp Neurol       Date:  2015-03-24       Impact factor: 5.330

4.  Priorities and Concerns for Research on Neurotrauma in the Developing World.

Authors:  Ali Razmkon
Journal:  Bull Emerg Trauma       Date:  2013-01

5.  Relationship between increases in pancreatic enzymes and cerebral events in children after traumatic brain injury.

Authors:  Joan Sanchez de Toledo; P David Adelson; R Scott Watson; Barbara Gaines; S Danielle Brown; Patrick M Kochanek; Stephen R Wisniewski; Ericka Fink; Hülya Bayir; Robert S B Clark; Michael J Bell
Journal:  Neurocrit Care       Date:  2009-12       Impact factor: 3.210

6.  Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury.

Authors:  Xinmin Wu; Hui Mao; Jiao Liu; Jian Xu; Jianhua Cao; Xingxing Gu; Gang Cui
Journal:  Int J Clin Exp Pathol       Date:  2013-06-15

Review 7.  Drug targets for traumatic brain injury from poly(ADP-ribose)polymerase pathway modulation.

Authors:  Valerie C Besson
Journal:  Br J Pharmacol       Date:  2009-04-09       Impact factor: 8.739

8.  Experimental diffuse brain injury results in regional alteration of gross vascular morphology independent of neuropathology.

Authors:  Jenna M Ziebell; Rachel K Rowe; Jordan L Harrison; Katharine C Eakin; Taylor Colburn; F Anthony Willyerd; Jonathan Lifshitz
Journal:  Brain Inj       Date:  2015-12-08       Impact factor: 2.311

9.  Alterations in enterocyte mitochondrial respiratory function and enzyme activities in gastrointestinal dysfunction following brain injury.

Authors:  Ke-Jun Zhu; Hong Huang; Hui Chu; Hang Yu; Shi-Ming Zhang
Journal:  World J Gastroenterol       Date:  2014-07-28       Impact factor: 5.742

10.  Severe traumatic head injury: prognostic value of brain stem injuries detected at MRI.

Authors:  A Hilario; A Ramos; J M Millan; E Salvador; P A Gomez; M Cicuendez; R Diez-Lobato; A Lagares
Journal:  AJNR Am J Neuroradiol       Date:  2012-05-10       Impact factor: 3.825

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.