Literature DB >> 17618850

TOR signaling and S6 kinase 1: Yeast catches up.

Ted Powers1.   

Abstract

Conservation of the rapamycin-sensitive TOR signaling network among eukaryotes has been instrumental to the rapid progress made in this field in recent years. A recent report in Molecular Cell (Urban et al., 2007) now extends this conservation to include Sch9, an AGC protein kinase family member from S. cerevisiae, which appears to be the long sought after yeast ortholog of mammalian S6 kinase 1 (S6K1) and a direct target for the rapamycin-sensitive TOR complex I.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17618850     DOI: 10.1016/j.cmet.2007.06.009

Source DB:  PubMed          Journal:  Cell Metab        ISSN: 1550-4131            Impact factor:   27.287


  23 in total

1.  Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.

Authors:  Brad J Niles; Huzefa Mogri; Andrew Hill; Ariadne Vlahakis; Ted Powers
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-17       Impact factor: 11.205

Review 2.  Replicative aging in yeast: the means to the end.

Authors:  K A Steinkraus; M Kaeberlein; B K Kennedy
Journal:  Annu Rev Cell Dev Biol       Date:  2008       Impact factor: 13.827

3.  Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway.

Authors:  Nicolas Talarek; Elisabetta Cameroni; Malika Jaquenoud; Xuan Luo; Séverine Bontron; Soyeon Lippman; Geeta Devgan; Michael Snyder; James R Broach; Claudio De Virgilio
Journal:  Mol Cell       Date:  2010-05-14       Impact factor: 17.970

4.  Ribosomal protein S6 phosphorylation is controlled by TOR and modulated by PKA in Candida albicans.

Authors:  Tahmeena Chowdhury; Julia R Köhler
Journal:  Mol Microbiol       Date:  2015-08-22       Impact factor: 3.501

5.  The TOR complex 1 is a direct target of Rho1 GTPase.

Authors:  Gonghong Yan; Yumei Lai; Yu Jiang
Journal:  Mol Cell       Date:  2012-03-22       Impact factor: 17.970

6.  A domain in the transcription activator Gln3 specifically required for rapamycin responsiveness.

Authors:  Rajendra Rai; Jennifer J Tate; Karthik Shanmuganatham; Martha M Howe; Terrance G Cooper
Journal:  J Biol Chem       Date:  2014-05-20       Impact factor: 5.157

Review 7.  Growth and aging: a common molecular mechanism.

Authors:  Mikhail V Blagosklonny; Michael N Hall
Journal:  Aging (Albany NY)       Date:  2009-04-20       Impact factor: 5.682

8.  A yeast-based genomic strategy highlights the cell protein networks altered by FTase inhibitor peptidomimetics.

Authors:  Giampiero Porcu; Cathal Wilson; Daniele Di Giandomenico; Antonella Ragnini-Wilson
Journal:  Mol Cancer       Date:  2010-07-23       Impact factor: 27.401

9.  Nuclear Gln3 Import Is Regulated by Nitrogen Catabolite Repression Whereas Export Is Specifically Regulated by Glutamine.

Authors:  Rajendra Rai; Jennifer J Tate; Karthik Shanmuganatham; Martha M Howe; David Nelson; Terrance G Cooper
Journal:  Genetics       Date:  2015-09-02       Impact factor: 4.562

10.  Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control.

Authors:  Kyoko Ikeda; Susumu Morigasaki; Hisashi Tatebe; Fuyuhiko Tamanoi; Kazuhiro Shiozaki
Journal:  Cell Cycle       Date:  2007-11-01       Impact factor: 4.534

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.