| Literature DB >> 17617697 |
Tomoo Hosoe1, Hideo Sakai, Makoto Ichikawa, Takeshi Itabashi, Takayuki Ishizaki, Ken-Ichi Kawai.
Abstract
In the course of screening for hyaluronidase (HAase) inhibitory agents, a new gamma-pyrone derivative, lepidepyrone, C(8)H(10)O(5), was isolated from the cultured mycelium of the mushroom Neolentinus lepideus TMC-1102 as a major HAase inhibitory compound (IC(50) 3.3 mM). The structure of lepidepyrone was established on the basis of spectroscopic investigation.Entities:
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Year: 2007 PMID： 17617697 DOI： 10.1038/ja.2007.53
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649