Literature DB >> 17617182

Antimicrobial susceptibilities of amoxycillin-non-susceptible and susceptible isolates among penicillin-non-susceptible Streptococcus pneumoniae.

E Pérez-Trallero1, J M Marimón, M Ercibengoa, M J Giménez, P Coronel, L Aguilar.   

Abstract

Antimicrobial susceptibilities of 244 amoxycillin-non-susceptible and 81 amoxycillin-susceptible pneumococcal isolates from 15 Spanish hospitals were determined and clonal relationships were investigated by pulsed-field gel electrophoresis after SmaI restriction. Amoxycillin-non-susceptible isolates exhibited higher rates of resistance to cefuroxime, cefixime, cefpodoxime and clarithromycin, but not to levofloxacin and cefotaxime. Cefditoren exhibited MIC(90) values one dilution lower than those of cefotaxime. Higher numbers of the Spain(14)-5 and Spain(6B)-2 clones, but not the Spain(9V)-3 and Spain(23F)-1 clones, were found among amoxycillin-non-susceptible isolates. Spain(14)-5 was the most problematic clone in terms of antibiotic resistance.

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Year:  2007        PMID: 17617182     DOI: 10.1111/j.1469-0691.2007.01777.x

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN: 1198-743X            Impact factor:   8.067


  6 in total

1.  Cidal activity of oral third-generation cephalosporins against Streptococcus pneumoniae in relation to cefotaxime intrinsic activity.

Authors:  F Cafini; L Aguilar; L Alou; M J Giménez; D Sevillano; M Torrico; N González; J J Granizo; J E Martín-Herrero; J Prieto
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-02-26       Impact factor: 3.267

2.  Influence of penicillin/amoxicillin non-susceptibility on the activity of third-generation cephalosporins against Streptococcus pneumoniae.

Authors:  A Fenoll; M J Giménez; O Robledo; L Aguilar; D Tarragó; J J Granizo; J E Martín-Herrero
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2007-10-18       Impact factor: 3.267

3.  Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates.

Authors:  Xiaoping Xu; Lin Cai; Meng Xiao; Fanrong Kong; Shahin Oftadeh; Fei Zhou; Gwendolyn L Gilbert
Journal:  Antimicrob Agents Chemother       Date:  2010-01-11       Impact factor: 5.191

Review 4.  Cefditoren in upper and lower community-acquired respiratory tract infections.

Authors:  Francisco Soriano; María-José Giménez; Lorenzo Aguilar
Journal:  Drug Des Devel Ther       Date:  2011-02-09       Impact factor: 4.162

5.  Drug resistance in community-acquired respiratory tract infections: role for an emerging antibacterial.

Authors:  Lorenzo Aguilar; María-José Giménez; José Barberán
Journal:  Infect Drug Resist       Date:  2010-06-18       Impact factor: 4.003

6.  High protein binding and cidal activity against penicillin-resistant S. pneumoniae: a cefditoren in vitro pharmacodynamic simulation.

Authors:  David Sevillano; Lorenzo Aguilar; Luis Alou; María-José Giménez; Natalia González; Martha Torrico; Fabio Cafini; Asunción Fenoll; Pilar Coronel; José Prieto
Journal:  PLoS One       Date:  2008-07-23       Impact factor: 3.240

  6 in total

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