Literature DB >> 17615841

A decade after the Tokyo sarin attack: a review of neurological follow-up of the victims.

Azik Hoffman1, Arik Eisenkraft, Arseny Finkelstein, Ophir Schein, Eran Rotman, Tsvika Dushnitsky.   

Abstract

OBJECTIVE: On March 20, 1995, sarin gas was used in Tokyo by members of the Japanese "Uhm-Shinrikiu" cult, killing 12 and injuring >5,500 innocent people. Most of the casualties were mildly injured. This article reviews the neurological follow-up data for some of the victims over the past decade.
METHODS: We reviewed the published literature regarding neurological follow-up of the victims, dividing the data according to the time elapsed after the attack.
RESULTS: The digit span test, finger-tapping test, and computerized posturography were the only performance tests that showed statistically significant differences between the victims and the control groups in some of the surveys. The main sequela 7 years after the attack was post-traumatic stress disorder.
CONCLUSIONS: The results emphasize the need for a national preparedness program for such mass casualty events, led by national health systems. This should include long-term, neurological, follow-up monitoring with performance tests and a post-traumatic stress disorder screening test.

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Year:  2007        PMID: 17615841     DOI: 10.7205/milmed.172.6.607

Source DB:  PubMed          Journal:  Mil Med        ISSN: 0026-4075            Impact factor:   1.437


  17 in total

1.  Spatiotemporal pattern of neuronal injury induced by DFP in rats: a model for delayed neuronal cell death following acute OP intoxication.

Authors:  Yonggang Li; Pamela J Lein; Cuimei Liu; Donald A Bruun; Teclemichael Tewolde; Gregory Ford; Byron D Ford
Journal:  Toxicol Appl Pharmacol       Date:  2011-04-12       Impact factor: 4.219

2.  The limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302.

Authors:  James P Apland; Vassiliki Aroniadou-Anderjaska; Taiza H Figueiredo; Franco Rossetti; Steven L Miller; Maria F M Braga
Journal:  J Pharmacol Exp Ther       Date:  2014-08-25       Impact factor: 4.030

3.  Pathophysiological mechanisms underlying increased anxiety after soman exposure: reduced GABAergic inhibition in the basolateral amygdala.

Authors:  Eric M Prager; Volodymyr I Pidoplichko; Vassiliki Aroniadou-Anderjaska; James P Apland; Maria F M Braga
Journal:  Neurotoxicology       Date:  2014-08-20       Impact factor: 4.294

4.  A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists.

Authors:  Steven L Miller; Vassiliki Aroniadou-Anderjaska; Taiza H Figueiredo; Eric M Prager; Camila P Almeida-Suhett; James P Apland; Maria F M Braga
Journal:  Toxicol Appl Pharmacol       Date:  2015-02-15       Impact factor: 4.219

5.  Chronic Treatment with Naltrexone Prevents Memory Retention Deficits in Rats Poisoned with the Sarin Analog Diisopropylfluorophosphate (DFP) and Treated with Atropine and Pralidoxime.

Authors:  Kori L Brewer; Tuan Tran; William J Meggs
Journal:  J Med Toxicol       Date:  2015-12

6.  Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain.

Authors:  Ronald B Pringle; Edward C Meek; Howard W Chambers; Janice E Chambers
Journal:  Toxicol Sci       Date:  2018-12-01       Impact factor: 4.849

7.  The recovery of acetylcholinesterase activity and the progression of neuropathological and pathophysiological alterations in the rat basolateral amygdala after soman-induced status epilepticus: relation to anxiety-like behavior.

Authors:  Eric M Prager; Vassiliki Aroniadou-Anderjaska; Camila P Almeida-Suhett; Taiza H Figueiredo; James P Apland; Franco Rossetti; Cara H Olsen; Maria F M Braga
Journal:  Neuropharmacology       Date:  2014-01-31       Impact factor: 5.250

Review 8.  The role of glutamate and the immune system in organophosphate-induced CNS damage.

Authors:  Arik Eisenkraft; Avshalom Falk; Arseny Finkelstein
Journal:  Neurotox Res       Date:  2013-03-27       Impact factor: 3.911

9.  Health implications of radiological terrorism: Perspectives from Israel.

Authors:  Moti Hagby; Avishay Goldberg; Steven Becker; Dagan Schwartz; Yaron Bar-Dayan
Journal:  J Emerg Trauma Shock       Date:  2009-05

10.  LY293558 prevents soman-induced pathophysiological alterations in the basolateral amygdala and the development of anxiety.

Authors:  Eric M Prager; Taiza H Figueiredo; Robert P Long; Vassiliki Aroniadou-Anderjaska; James P Apland; Maria F M Braga
Journal:  Neuropharmacology       Date:  2014-09-06       Impact factor: 5.250

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