OBJECTIVE: To evaluate the long-term outcome after decompressive surgery in dogs with degenerative lumbosacral stenosis (DLS), using force plate analysis (FPA) and owner questionnaires. STUDY DESIGN: Prospective clinical study. ANIMALS: Dogs with DLS (n=31) and 24 clinically normal Labrador Retrievers. METHODS: FPA was performed before surgery (31 dogs) and at 3 days, 6 weeks, 6 months (each, 31 dogs) and >or=1.5 years (12 dogs) after surgery. Peak vertical forces (Fz(+)), braking (Fy(+)), and propulsive forces (Fy(-)), and the corresponding impulses were determined. Questionnaires were completed by the owners before and at 6 months and >or=1.5 years after surgery. RESULTS: Fy(-) of the pelvic limbs and the ratio pelvic/thoracic of Fy(-) (P/TFy(-)) were significantly smaller in dogs with DLS than controls. Fy(-) and P/TFy(-) decreased significantly 3 days after surgery, and increased during 6 months follow-up, but with long-term follow-up the values remained the same and were smaller than controls. From questionnaires there was a significant improvement after surgery compared with function before surgery. Most owners were satisfied with outcome after surgery. CONCLUSIONS: Propulsive forces of the pelvic limbs in dogs with DLS are impaired and are partially restored by decompressive surgery. CLINICAL RELEVANCE: Owner's questionnaires illustrate that decompressive surgery restores function as perceived by owners whereas FPA continues to show impaired propulsive forces for the pelvic limbs.
OBJECTIVE: To evaluate the long-term outcome after decompressive surgery in dogs with degenerative lumbosacral stenosis (DLS), using force plate analysis (FPA) and owner questionnaires. STUDY DESIGN: Prospective clinical study. ANIMALS: Dogs with DLS (n=31) and 24 clinically normal Labrador Retrievers. METHODS: FPA was performed before surgery (31 dogs) and at 3 days, 6 weeks, 6 months (each, 31 dogs) and >or=1.5 years (12 dogs) after surgery. Peak vertical forces (Fz(+)), braking (Fy(+)), and propulsive forces (Fy(-)), and the corresponding impulses were determined. Questionnaires were completed by the owners before and at 6 months and >or=1.5 years after surgery. RESULTS: Fy(-) of the pelvic limbs and the ratio pelvic/thoracic of Fy(-) (P/TFy(-)) were significantly smaller in dogs with DLS than controls. Fy(-) and P/TFy(-) decreased significantly 3 days after surgery, and increased during 6 months follow-up, but with long-term follow-up the values remained the same and were smaller than controls. From questionnaires there was a significant improvement after surgery compared with function before surgery. Most owners were satisfied with outcome after surgery. CONCLUSIONS: Propulsive forces of the pelvic limbs in dogs with DLS are impaired and are partially restored by decompressive surgery. CLINICAL RELEVANCE: Owner's questionnaires illustrate that decompressive surgery restores function as perceived by owners whereas FPA continues to show impaired propulsive forces for the pelvic limbs.
Authors: Anna Tellegen; Martijn Beukers; Imke Rudnik-Jansen; Nicolien van Klaveren; Kan Loi How; Nina Woike; George Mihov; Jens Thies; Erik Teske; Laura Creemers; Marianna Tryfonidou; Björn Meij Journal: Pharmaceutics Date: 2021-03-11 Impact factor: 6.321
Authors: Koen Willemsen; Marianna A Tryfonidou; Ralph J B Sakkers; René M Castelein; Martijn Beukers; Peter R Seevinck; Harrie Weinans; Bart C H van der Wal; Björn P Meij Journal: Sci Rep Date: 2022-02-22 Impact factor: 4.379
Authors: Thomas R Harcourt-Brown; Nicolas P Granger; Noel Fitzpatrick; Nicholas D Jeffery Journal: J Vet Intern Med Date: 2019-08-05 Impact factor: 3.333