Literature DB >> 17612976

Cutaneous and ocular late complications of sulfur mustard in Iranian veterans.

Majid Shohrati1, Mohammadreza Peyman, Alireza Peyman, Masoud Davoudi, Mostafa Ghanei.   

Abstract

Although sulfur mustard (SM) has been used as a chemical warfare agent since the early twentieth century, it has reemerged in the past decade as a major threat around the world. This agent injured over 100,000 Iranians and one-third is suffering from late effects until today. Mustard affects many organs such as the skin, eyes, and lungs, as well as the gastrointestinal, endocrine, and hematopoietic system. In this study we focused on review of the late Cutaneous and ocular complications caused by exposure to SM. All studies regarding long-term ocular and cutaneous effects, which have been done on Iranian population, were collected from domestic and international sources. Pruritus is the most common complain and a malignant change is the most important lesion, which has to be considered. Also this agent is causes of chronic and delayed destructive lesions in the ocular surface and cornea, leading to progressive visual deterioration and ocular irritation.

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Year:  2007        PMID: 17612976     DOI: 10.1080/15569520701212399

Source DB:  PubMed          Journal:  Cutan Ocul Toxicol        ISSN: 1556-9527            Impact factor:   1.820


  20 in total

Review 1.  Cellular and molecular mechanisms of sulfur mustard toxicity on spermatozoa and male fertility.

Authors:  Asghar Beigi Harchegani; Mahdiyeh Mirnam Niha; Milad Sohrabiyan; Mahdi Ghatrehsamani; Eisa Tahmasbpour; Alireza Shahriary
Journal:  Toxicol Res (Camb)       Date:  2018-07-09       Impact factor: 3.524

2.  Doxycycline hydrogels as a potential therapy for ocular vesicant injury.

Authors:  Marion K Gordon; Andrea Desantis; Manjeet Deshmukh; Carl Jeffrey Lacey; Rita A Hahn; John Beloni; Sivanaga S Anumolu; John J Schlager; Michael A Gallo; Donald R Gerecke; Ned D Heindel; Kathy K H Svoboda; Michael C Babin; Patrick J Sinko
Journal:  J Ocul Pharmacol Ther       Date:  2010-10       Impact factor: 2.671

Review 3.  Phosgene oxime: Injury and associated mechanisms compared to vesicating agents sulfur mustard and lewisite.

Authors:  Dinesh Giri Goswami; Rajesh Agarwal; Neera Tewari-Singh
Journal:  Toxicol Lett       Date:  2017-11-12       Impact factor: 4.372

4.  Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.

Authors:  Swetha Inturi; Neera Tewari-Singh; Mallikarjuna Gu; Sangeeta Shrotriya; Joe Gomez; Chapla Agarwal; Carl W White; Rajesh Agarwal
Journal:  Free Radic Biol Med       Date:  2011-08-26       Impact factor: 7.376

5.  Doxycycline hydrogels with reversible disulfide crosslinks for dermal wound healing of mustard injuries.

Authors:  SivaNaga S Anumolu; Anupa R Menjoge; Manjeet Deshmukh; Donald Gerecke; Stanley Stein; Jeffrey Laskin; Patrick J Sinko
Journal:  Biomaterials       Date:  2010-10-14       Impact factor: 12.479

6.  Topical nitrogen mustard exposure causes systemic toxic effects in mice.

Authors:  Dinesh G Goswami; Dileep Kumar; Neera Tewari-Singh; David J Orlicky; Anil K Jain; Rama Kant; Raymond C Rancourt; Deepanshi Dhar; Swetha Inturi; Chapla Agarwal; Carl W White; Rajesh Agarwal
Journal:  Exp Toxicol Pathol       Date:  2014-12-04

7.  Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results.

Authors:  Ahmet Korkmaz; Hakan Yaren; Z Ilker Kunak; Bulent Uysal; Bulent Kurt; Turgut Topal; Levent Kenar; Ergun Ucar; Sukru Oter
Journal:  Interdiscip Toxicol       Date:  2008-12

8.  Mustard vesicants alter expression of the endocannabinoid system in mouse skin.

Authors:  Irene M Wohlman; Gabriella M Composto; Diane E Heck; Ned D Heindel; C Jeffrey Lacey; Christophe D Guillon; Robert P Casillas; Claire R Croutch; Donald R Gerecke; Debra L Laskin; Laurie B Joseph; Jeffrey D Laskin
Journal:  Toxicol Appl Pharmacol       Date:  2016-04-26       Impact factor: 4.219

9.  Long-term complications of sulphur mustard poisoning in intoxicated Iranian veterans.

Authors:  Soha Namazi; Hosein Niknahad; Hasan Razmkhah
Journal:  J Med Toxicol       Date:  2009-12

10.  Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.

Authors:  Swetha Inturi; Neera Tewari-Singh; Chapla Agarwal; Carl W White; Rajesh Agarwal
Journal:  Mutat Res       Date:  2014-04-13       Impact factor: 2.433

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