Literature DB >> 17611931

Inhibitory constituents of Euscaphis japonica on lipopolysaccharide-induced nitric oxide production in BV2 microglia.

Mi Kyeong Lee1, Hee Young Jeon, Ki Yong Lee, Seung Hyun Kim, Choong Je Ma, Sang Hyun Sung, Heum-Sook Lee, Mi Jung Park, Young Choong Kim.   

Abstract

Bioactivity-guided fractionation of the methanolic extract of the aerial parts of EUSCAPHIS JAPONICA (Tunb.) Kantiz (Staphyleaceae), afforded a new compound, P-coumaroyl- D-malic acid 1-methyl ester (1), together with twelve known compounds, 3,7-dihydro-5-octanolide (2), blumenol A (3), megastigmane (4), gallic acid (5), stenophyllin H1 (6), methyl 5,7-dihydroxyoctanoate (7), TRANS-phytol (8), alpha-tocopherol (9), kaempferol (10), kaempferol 3-O-beta-D-glucopyranoside (11), quercetin (12) and quercetin 3-O-beta-D-glucopyranoside (13). Among them, compounds 1 - 5 and 8 - 13 significantly inhibited lipopolysacchride-induced nitric oxide production in murine BV2 microglial cells. Especially, compounds 5, 8, 10 and 12 exerted potent inhibitory activity comparable to that of NAME, used as positive control.

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Year:  2007        PMID： 17611931     DOI： 10.1055/s-2007-981551

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  6 in total

1.  Antimicrobial Air Filters Using Natural Euscaphis japonica Nanoparticles.

Authors:  Gi Byoung Hwang; Ki Joon Heo; Ji Ho Yun; Jung Eun Lee; Hee Ju Lee; Chu Won Nho; Gwi-Nam Bae; Jae Hee Jung
Journal:  PLoS One       Date:  2015-05-14       Impact factor: 3.240

2.  Selection and evaluation of reference genes for qRT-PCR analysis in Euscaphis konishii Hayata based on transcriptome data.

Authors:  Wenxian Liang; Xiaoxing Zou; Rebeca Carballar-Lejarazú; Lingjiao Wu; Weihong Sun; Xueyuan Yuan; Songqing Wu; Pengfei Li; Hui Ding; Lin Ni; Wei Huang; Shuangquan Zou
Journal:  Plant Methods       Date:  2018-06-04       Impact factor: 4.993

3.  Attenuation of Inflammatory Symptoms by Icariside B2 in Carrageenan and LPS-Induced Inflammation Models via Regulation of MAPK/NF-κB Signaling Cascades.

Authors:  Md Badrul Alam; Yoon-Gyung Kwon; Shakina Yesmin Simu; Sk Abrar Shahriyar; Sang Han Lee
Journal:  Biomolecules       Date:  2020-07-11

4.  Comparative transcriptome among Euscaphis konishii Hayata tissues and analysis of genes involved in flavonoid biosynthesis and accumulation.

Authors:  Wenxian Liang; Lin Ni; Rebeca Carballar-Lejarazú; Xiaoxing Zou; Weihong Sun; Lingjiao Wu; Xueyuan Yuan; Yanling Mao; Wei Huang; Shuangquan Zou
Journal:  BMC Genomics       Date:  2019-01-09       Impact factor: 3.969

5.  The aqueous extract from Toona sinensis leaves inhibits microglia-mediated neuroinflammation.

Authors:  Chao-Chuan Wang; Yee-Jean Tsai; Ya-Ching Hsieh; Rong-Jyh Lin; Chih-Lung Lin
Journal:  Kaohsiung J Med Sci       Date:  2013-11-01       Impact factor: 2.744

6.  Metabolome-based profiling of African baobab fruit (Adansonia digitata L.) using a multiplex approach of MS and NMR techniques in relation to its biological activity.

Authors:  Mostafa H Baky; Marwa T Badawy; Alaa F Bakr; Nesrine M Hegazi; Ahmed Abdellatif; Mohamed A Farag
Journal:  RSC Adv       Date:  2021-12-13       Impact factor: 4.036
  6 in total

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