Literature DB >> 17610952

Current knowledge on lower virulence of Reston Ebola virus (in French: Connaissances actuelles sur la moindre virulence du virus Ebola Reston).

Shigeru Morikawa1, Masayuki Saijo, Ichiro Kurane.   

Abstract

Ebola viruses (EBOV) and Marburg virus belong to the family Filoviridae, order Mononegavirales. The genus Ebolavirus consists of four species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Ivory Coast ebolavirus (ICEBOV) and Reston ebolavirus (REBOV). Three species of ebolaviruses, ZEBOV, SEBOV, ICEBOV, and Marburg virus are known to be extremely pathogenic in primates and humans and cause severe hemorrhagic fever leading up to case fatality rate of some 90%, while REBOV is thought to be pathogenic in Asian monkeys but not in African monkeys and humans. Recent studies indicated several factors involved in different virulence between African EBOV and REBOV. This article reviews the history, epidemiology, and virulence of REBOV.

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Year:  2007        PMID： 17610952     DOI： 10.1016/j.cimid.2007.05.005

Source DB:  PubMed          Journal:  Comp Immunol Microbiol Infect Dis        ISSN： 0147-9571            Impact factor:   2.268


  18 in total

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