Literature DB >> 17610554

Fracture neck of femur in haemophilia A - experience from a cohort of 11 patients from a tertiary centre in India.

V N Lee1, A Srivastava, M Nithyananth, P Kumar, V M Cherian, A Viswabandya, V Mathews, B George, K Venkatesh, S C Nair, M Chandy, G D Sundararaj.   

Abstract

We describe here the management of eleven patients with fracture neck of femur. Excepting one patient all had severe haemophilia A. Nine patients were less than 50 years of age. Eight out of eleven patients had fracture after trivial trauma. Nine patients had closed reduction and one patient open reduction. The patient with non union had a Valgus osteotomy. All fractures united. The average time to union was 11 weeks (range:8-16). We followed either a low dose intermittent or a low dose continuous infusion factor support protocol for the management of these patients. The median dose of factor support was 252 u/kg (range: 136-580). The average duration of factor support was 9 days (range: 7-10). Two patients had aggravation of pre existing knee stiffness following post operative immobilisation. No other major complication was observed in this cohort of patients. To conclude, management of fracture neck of femur in patients with haemophilia is no different from general population if an adequate haemostasis is achieved.

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Year:  2007        PMID: 17610554     DOI: 10.1111/j.1365-2516.2007.01448.x

Source DB:  PubMed          Journal:  Haemophilia        ISSN: 1351-8216            Impact factor:   4.287


  5 in total

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Authors:  Hassan Mansouritorghabeh; Zahra Rezaieyazdi
Journal:  Rheumatol Int       Date:  2010-05-27       Impact factor: 2.631

2.  Management of Haemophilia in Developing Countries: Challenges and Options.

Authors:  Kanjaksha Ghosh; Kinjalka Ghosh
Journal:  Indian J Hematol Blood Transfus       Date:  2015-06-18       Impact factor: 0.900

3.  Hemophilia care in India: a review and experience from a tertiary care centre in uttar pradesh.

Authors:  Shubha Phadke
Journal:  Indian J Hematol Blood Transfus       Date:  2011-07-12       Impact factor: 0.900

Review 4.  Osteoporosis management and falls prevention in patients with haemophilia: Review of haemophilia guidelines.

Authors:  Madison J Petkovic; Huyen A Tran; Peter R Ebeling; Ayse Zengin
Journal:  Haemophilia       Date:  2022-03-15       Impact factor: 4.263

5.  Fracture neck of femur in Factor XIII deficiency: Was better outcome possible?

Authors:  Sandeep Vijayan; Harish Pai; Hitesh Shah; Nalini Bhaskaranand
Journal:  J Family Med Prim Care       Date:  2017 Jul-Sep
  5 in total

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