Literature DB >> 17609925

[Low-dose rate brachytherapy with locally integrated beta emitters after internal urethrotomy. A pilot project using an animal model].

P Weidlich1, C Adam, R Sroka, I Lanzl, W Assmann, C Stief.   

Abstract

BACKGROUND: The treatment of urethral strictures represents an unsolved urological problem. PATIENTS AND METHODS: The effect of a (32)P-coated urethral catheter in the sense of low-dose rate brachytherapy to modulate wound healing will be analyzed in an animal experiment.
RESULTS: Unfortunately it is not possible to present any results because this is being studied for the first time and there are no experiences with low-dose rate brachytherapy and this form of application in the lower urinary tract. Furthermore the animal experiment will only start in the near future. Both decade-long experiences with radiotherapy to treat benign diseases and our own results of previous studies in otolaryngology and ophthalmology let us expect a significantly lower formation of urethral strictures after internal urethrotomy.
CONCLUSION: This study will contribute to improving the treatment of urethral strictures as demanded in previous papers.

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Year:  2007        PMID: 17609925     DOI: 10.1007/s00120-007-1386-6

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  18 in total

1.  Core through urethrotomy with the neodymium:YAG laser for posttraumatic obliterative strictures of the bulbomembranous urethra.

Authors:  P N Dogra; M Aron; T P Rajeev
Journal:  J Urol       Date:  1999-01       Impact factor: 7.450

2.  Internal urethrotomy in the management of anterior urethral strictures: long-term followup.

Authors:  V Pansadoro; P Emiliozzi
Journal:  J Urol       Date:  1996-07       Impact factor: 7.450

3.  Long-term results of internal urethrotomy.

Authors:  P Albers; J Fichtner; P Brühl; S C Müller
Journal:  J Urol       Date:  1996-11       Impact factor: 7.450

Review 4.  [Alternative endourologic methods for treatment of urethral stricture].

Authors:  T Niesel; R G Moore; R Hofmann; L R Kavoussi
Journal:  Urologe A       Date:  1998-01       Impact factor: 0.639

5.  Intraurethral brachytherapy for prevention of recurrent urethral stricture after internal urethrotomy or transurethral resection of scar.

Authors:  Y H Sun; C L Xu; X Gao; Y N Jin; L H Wang; G Q Liao; Z F Wang; J G Hou; S X Qian; M A Yong-Jiang
Journal:  J Endourol       Date:  2001-10       Impact factor: 2.942

Review 6.  [Laser treatment of urethral strictures].

Authors:  R Klammert; P Schneede; M Kriegmair
Journal:  Urologe A       Date:  1994-07       Impact factor: 0.639

7.  Visual internal urethrotomy with postoperative cystostomy or urethral catheter.

Authors:  B Asklin; S Pettersson
Journal:  Scand J Urol Nephrol       Date:  1983

8.  Internal urethrotomy versus dilation as treatment for male urethral strictures: a prospective, randomized comparison.

Authors:  J W Steenkamp; C F Heyns; M L de Kock
Journal:  J Urol       Date:  1997-01       Impact factor: 7.450

9.  The use of halofuginone in limiting urethral stricture formation and recurrence: an experimental study in rabbits.

Authors:  Mehdi Jaidane; Bedeir Ali-El-Dein; Abdelahad Ounaies; Ashraf T Hafez; Tarek Mohsen; Mahmoud Bazeed
Journal:  J Urol       Date:  2003-11       Impact factor: 7.450

10.  An experimental model for stricture studies in the anterior urethra of the male rabbit.

Authors:  H L Andersen; B U Duch; J B Nielsen; B Joergensen; T Ledet
Journal:  Urol Res       Date:  2003-10-01
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  1 in total

1.  Development and pre-clinical test of a phosphorous-32 containing polyetheretherketone foil aiming at urethral stricture prevention by low-dose-rate brachytherapy.

Authors:  Walter Assmann; Ricarda Becker; Christian Stief; Ronald Sroka
Journal:  J Contemp Brachytherapy       Date:  2022-04-02
  1 in total

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