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Literature DB >> 17609790

Rescue of the streptomycin antibiotic activity by using streptidine as a "decoy acceptor" for the aminoglycoside-inactivating enzyme adenyl transferase.

Montserrat Latorre¹, Pablo Peñalver, Julia Revuelta, Juan Luis Asensio, Eduardo García-Junceda, Agatha Bastida.

Abstract

The use of streptidine as a "decoy acceptor" allows the antibiotic activity of streptomycin to recover against the Escherichia coli strain overexpressing the aminoglycoside-modifying enzyme 6-O-adenyl transferase.

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Year: 2007 PMID： 17609790 DOI： 10.1039/b704785a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

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Cited

2 in total

1. Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis.

Authors: Keith D Green; Ankita Punetha; Caixia Hou; Sylvie Garneau-Tsodikova; Oleg V Tsodikov
Journal: ACS Infect Dis Date: 2019-08-21 Impact factor: 5.084

Review 2. Overcoming Aminoglycoside Enzymatic Resistance: Design of Novel Antibiotics and Inhibitors.

Authors: Sandra G Zárate; M Luisa De la Cruz Claure; Raúl Benito-Arenas; Julia Revuelta; Andrés G Santana; Agatha Bastida
Journal: Molecules Date: 2018-01-30 Impact factor: 4.411

2 in total