Literature DB >> 17609644

Marijuana: an effective antiepileptic treatment in partial epilepsy? A case report and review of the literature.

Katherine Mortati1, Barbara Dworetzky, Orrin Devinsky.   

Abstract

Although more data are needed, animal studies and clinical experience suggest that marijuana or its active constituents may have a place in the treatment of partial epilepsy. Here we present the case of a 45-year-old man with cerebral palsy and epilepsy who showed marked improvement with the use of marijuana. This case supports other anecdotal data suggesting that marijuana use may be a beneficial adjunctive treatment in some patients with epilepsy. Although challenging because of current federal regulations, further studies are needed to examine the role of marijuana in the treatment of this disorder.

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Year:  2007        PMID: 17609644

Source DB:  PubMed          Journal:  Rev Neurol Dis        ISSN: 1545-2913


  7 in total

Review 1.  Plant-Derived and Endogenous Cannabinoids in Epilepsy.

Authors:  Alberto Verrotti; Miriam Castagnino; Mauro Maccarrone; Filomena Fezza
Journal:  Clin Drug Investig       Date:  2016-05       Impact factor: 2.859

Review 2.  Cannabinoids and Epilepsy.

Authors:  Evan C Rosenberg; Richard W Tsien; Benjamin J Whalley; Orrin Devinsky
Journal:  Neurotherapeutics       Date:  2015-10       Impact factor: 7.620

3.  The secret "spice": an undetectable toxic cause of seizure.

Authors:  Adam de Havenon; Brian Chin; Karen C Thomas; Pegah Afra
Journal:  Neurohospitalist       Date:  2011-10

Review 4.  Cannabinoids for epilepsy.

Authors:  David Gloss; Barbara Vickrey
Journal:  Cochrane Database Syst Rev       Date:  2014-03-05

Review 5.  Medical Use of Cannabinoids.

Authors:  Ana Isabel Fraguas-Sánchez; Ana Isabel Torres-Suárez
Journal:  Drugs       Date:  2018-11       Impact factor: 9.546

6.  A spicy status: Synthetic cannabinoid (spice) use and new-onset refractory status epilepticus-A case report and review of the literature.

Authors:  Marc-Alain Babi; Christopher P Robinson; Carolina B Maciel
Journal:  SAGE Open Med Case Rep       Date:  2017-12-05

Review 7.  Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?

Authors:  Emilio Perucca
Journal:  J Epilepsy Res       Date:  2017-12-31
  7 in total

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