Literature DB >> 17609168

Production of optically active 1,2,4-butanetriol from corresponding racemate by Microbial stereoinversion.

Keiko Yamada-Onodera1, Akihiro Norimoto, Naoki Kawada, Rika Furuya, Hiroaki Yamamoto, Yoshiki Tani.   

Abstract

Sterigmatomyces elviae DSM 70852 produced 12 g/l (S)-1,2,4-butanetriol (enantiomeric excess >99.9%) from 20 g/l racemate in 82 h. From the results of the inversion of an (R)-isomer to an (S)-isomer and GC-MS, it was suggested that (R)-1,2,4-butanetriol is oxidized to 1,4-dihydroxy-2-butanone, which is reduced to an (S)-isomer.

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Year:  2007        PMID: 17609168     DOI: 10.1263/jbb.103.494

Source DB:  PubMed          Journal:  J Biosci Bioeng        ISSN: 1347-4421            Impact factor:   2.894


  2 in total

1.  The Biosynthesis of D-1,2,4-Butanetriol From d-Arabinose With an Engineered Escherichia coli.

Authors:  Jing Wang; Qiaoyu Chen; Xin Wang; Kequan Chen; Pingkai Ouyang
Journal:  Front Bioeng Biotechnol       Date:  2022-03-24

2.  Design and construction of a non-natural malate to 1,2,4-butanetriol pathway creates possibility to produce 1,2,4-butanetriol from glucose.

Authors:  Xinghua Li; Zhen Cai; Yin Li; Yanping Zhang
Journal:  Sci Rep       Date:  2014-07-10       Impact factor: 4.379

  2 in total

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