Literature DB >> 176055

Does an inhibitor of mitochondrial adenylate kinase also affect oxidative phosphorylation?

J Lüstorff, E Schlimme.   

Abstract

Adenylate kinase activity of intact mitochondria is strongly inhibited by Ap5A, i.e. p1,p5-Di (adenosine-5') pentaphosphate, whereas oxidative phosphorylation is not affected. Therefore, Ap5A is a useful tool to distinguish between oxidative and non oxidative ATP generating reactions.

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Year:  1976        PMID： 176055     DOI： 10.1007/bf01940801

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  Techniques for the application of polarography to mitochondrial respiration.

Authors:  B HAGIHARA
Journal:  Biochim Biophys Acta       Date:  1961-01-01

2.  Intramitochondrial intermembranal large amplitude protein movements. I. A possible novel aspect of membrane fluidity.

Authors:  A Waksman; A Rendon
Journal:  Biochimie       Date:  1974       Impact factor: 4.079

3.  P 1 ,P 5 -Di(adenosine-5')pentaphosphate, a potent multisubstrate inhibitor of adenylate kinase.

Authors:  G E Lienhard; I I Secemski
Journal:  J Biol Chem       Date:  1973-02-10       Impact factor: 5.157

4.  Adenosine monophosphate as the first phosphoryl acceptor in oxidative phosphorylation.

Authors:  T Ozawa
Journal:  Arch Biochem Biophys       Date:  1966-11       Impact factor: 4.013

5.  Phosphorylation of bound adenosine monophosphate in the electron transfer particle, driven by succinate.

Authors:  T Ozawa; D H MacLennan
Journal:  Biochem Biophys Res Commun       Date:  1965-12-21       Impact factor: 3.575
  5 in total
  2 in total

1.  Stoichiometry of vectorial H+ movements coupled to electron transport and to ATP synthesis in mitochondria.

Authors:  A Alexandre; B Reynafarje; A L Lehninger
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

2.  Overexpressing superoxide dismutase 2 induces a supernormal cardiac function by enhancing redox-dependent mitochondrial function and metabolic dilation.

Authors:  Patrick T Kang; Chwen-Lih Chen; Vahagn Ohanyan; Daniel J Luther; J Gary Meszaros; William M Chilian; Yeong-Renn Chen
Journal:  J Mol Cell Cardiol       Date:  2015-09-12       Impact factor: 5.000
  2 in total

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