Literature DB >> 17604714

The X factor: skewing X inactivation towards cancer.

René H Medema1, Boudewijn M Th Burgering.   

Abstract

Increased expression of the epidermal growth factor receptor HER-2/ErbB2 is frequently observed in breast cancer and is targeted by the anticancer drug Herceptin. Now, Zuo et al. (2007) reveal that an X-linked gene encoding the transcription factor FOXP3 is a breast cancer tumor suppressor that represses expression of HER2/ErbB2.

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Year:  2007        PMID： 17604714     DOI： 10.1016/j.cell.2007.06.008

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  14 in total

1.  The relationship between skewed X chromosome inactivation and the prognosis of Graves' and Hashimoto's diseases.

Authors:  Naoko Ishido; Naoya Inoue; Mikio Watanabe; Yoh Hidaka; Yoshinori Iwatani
Journal:  Thyroid       Date:  2014-12-10       Impact factor: 6.568

2.  Characterization of human invariant natural killer T cells expressing FoxP3.

Authors:  Péter Engelmann; Klára Farkas; János Kis; Geoffrey Richman; Zhaoyun Zhang; Chong Wee Liew; Maciej Borowiec; Monika A Niewczas; Heyam Jalahej; Tihamér Orbán
Journal:  Int Immunol       Date:  2011-06-27       Impact factor: 4.823

Review 3.  Inactivation of X-linked tumor suppressor genes in human cancer.

Authors:  Runhua Liu; Mandy Kain; Lizhong Wang
Journal:  Future Oncol       Date:  2012-04       Impact factor: 3.404

4.  BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation.

Authors:  Wen-Yi Yu; Yu Zhang; Meng-Kai Li; Zi-Ying Yang; Wing Kam Fung; Pei-Zhen Zhao; Ji-Yuan Zhou
Journal:  BMC Bioinformatics       Date:  2022-05-24       Impact factor: 3.307

Review 5.  X chromosome regulation: diverse patterns in development, tissues and disease.

Authors:  Xinxian Deng; Joel B Berletch; Di K Nguyen; Christine M Disteche
Journal:  Nat Rev Genet       Date:  2014-04-15       Impact factor: 53.242

Review 6.  IGF2: epigenetic regulation and role in development and disease.

Authors:  Wendy Chao; Patricia A D'Amore
Journal:  Cytokine Growth Factor Rev       Date:  2008-03-04       Impact factor: 7.638

7.  Stochastic epigenetic mutations (DNA methylation) increase exponentially in human aging and correlate with X chromosome inactivation skewing in females.

Authors:  Davide Gentilini; Paolo Garagnani; Serena Pisoni; Maria Giulia Bacalini; Luciano Calzari; Daniela Mari; Giovanni Vitale; Claudio Franceschi; Anna Maria Di Blasio
Journal:  Aging (Albany NY)       Date:  2015-08       Impact factor: 5.682

8.  High frequency of the X-chromosome inactivation in young female patients with high-grade glioma.

Authors:  Gang Li; Zhiguo Zhang; Tianbo Jin; Hongjuan Liang; Yanyang Tu; Li Gong; Zhongping Chen; Guodong Gao
Journal:  Diagn Pathol       Date:  2013-06-19       Impact factor: 2.644

9.  The haplotype of three polymorphisms in the SATB1 promoter region impacts survival in breast cancer patients.

Authors:  Martin Heubner; Rainer Kimmig; Bahriye Aktas; Winfried Siffert; Ulrich H Frey
Journal:  Oncol Lett       Date:  2014-03-20       Impact factor: 2.967

10.  Skewed X-chromosome inactivation in patients with esophageal carcinoma.

Authors:  Gang Li; Tianbo Jin; Hongjuan Liang; Yanyang Tu; Wei Zhang; Li Gong; Qin Su; Guodong Gao
Journal:  Diagn Pathol       Date:  2013-04-04       Impact factor: 2.644
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